60594-68-5

Upstream product

• 82259-21-0 7-(3-methylthio-1-oxo-6,10-dithiaspiro<4.5>dec-2-en-2-yl)-heptanoic acid 
• 82259-22-1 methyl 7-(3-oxo-6,10-dithiaspiro<4.5>dec-1-en-2-yl)heptanoate 
• 21269-27-2 (+/-)-15-epi-11-deoxyprostaglandin E₁ 
• 82259-23-2 7-{(1R,2R)-1-[(E)-3-(tert-Butyl-dimethyl-silanyloxy)-oct-1-enyl]-3-oxo-6,10-dithia-spiro[4.5]dec-2-yl}-heptanoic acid methyl ester 
• 82259-24-3 7-{1-[(E)-3-(tert-Butyl-dimethyl-silanyloxy)-oct-1-enyl]-3-hydroxy-6,10-dithia-spiro[4.5]dec-2-yl}-heptanoic acid methyl ester 
• 95448-81-0 7-{3-Acetoxy-1-[(E)-3-(tert-butyl-dimethyl-silanyloxy)-oct-1-enyl]-6,10-dithia-spiro[4.5]dec-2-yl}-heptanoic acid methyl ester 
• 5239-48-5 7-[(1S,2S,5S)-2-Hydroxy-5-((E)-(R)-3-hydroxy-oct-1-enyl)-cyclopentyl]-heptanoic acid methyl ester 
• 34603-80-0 15α-hydroxy-11-deoxy-8α,12β-prostaglandin-E₁ 
• 5239-48-5 7-[(1S,2R,5S)-2-Hydroxy-5-((E)-(R)-3-hydroxy-oct-1-enyl)-cyclopentyl]-heptanoic acid methyl ester 
• 33782-53-5 7-[2-oxo-5-(3-oxo-1-octenyl)cyclopentyl]heptanoic acid 

Relevant academic research and scientific papers

TOTAL SYNTHESIS OF PROSTAGLANDIN D1 METHYL ESTER AND 9-EPI-PROSTAGLANDIN D1 METHYL ESTER

Synthesis of the title compounds are described via the dithiane enone (VIII); cuprate addition to (VIII) proceeds with asymmetric induction.

Lithium 3-triphenylmethoxy-1-trans-alkenyl-dialkyl alanates

This disclosure describes 3-triphenylmethoxy-1-alkynes, 3-triphenylmethoxy-1-trans-alkenyl-dialkyl-alanes, and lithium 3-triphenylmethoxy-1-trans-alkenyl-dialkyl alanates useful as intermediates for the preparation of certain 11-hydroxy- and 11-deoxy-9-keto(or hydroxy)-prostanoic acid derivatives which possess bronchodilator, hypotensive, and anti-ulcer activity.

Cyclopentane derivatives

Cyclopentane derivatives of the prostaglandin type of the formula: SPC1 (wherein R1 represents hydrogen or lower alkyl, R2 represents alkyl of 1 to 10 carbon atoms, the symbols R3 are the same and represent hydrogen, lower