60597-72-0 Usage
Uses
Used in Pharmaceutical Industry:
4-[(2-Chloropyridin-3-yl)sulphonyl]morpholine is used as a potential pharmaceutical compound for its possible bioactivity resulting from the interaction of morpholine, 2-chloropyridine, and the sulfonyl linker. The specific application reason would depend on the experimental data or safety datasheets that provide information about its toxicity, health risks, and effectiveness in various pharmaceutical applications.
Used in Chemical Research:
4-[(2-Chloropyridin-3-yl)sulphonyl]morpholine is used as a research compound in the field of organic chemistry, particularly for studying the properties and reactions of sulfones, pyridines, and morpholines. 4-[(2-Chloropyridin-3-yl)sulphonyl]morpholine's unique structure and potential reactivity make it a valuable subject for understanding the chemical characteristics and interactions of these components.
Used in Industrial Applications:
4-[(2-Chloropyridin-3-yl)sulphonyl]morpholine may be used as an intermediate or a building block in the synthesis of other complex organic compounds for various industrial applications. 4-[(2-Chloropyridin-3-yl)sulphonyl]morpholine's potential use in this context would be determined by its chemical properties, reactivity, and compatibility with other compounds in the synthesis process.
Check Digit Verification of cas no
The CAS Registry Mumber 60597-72-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,5,9 and 7 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 60597-72:
(7*6)+(6*0)+(5*5)+(4*9)+(3*7)+(2*7)+(1*2)=140
140 % 10 = 0
So 60597-72-0 is a valid CAS Registry Number.
InChI:InChI=1/C9H11ClN2O3S/c10-9-8(2-1-3-11-9)16(13,14)12-4-6-15-7-5-12/h1-3H,4-7H2
60597-72-0Relevant academic research and scientific papers
A novel series of [1,2,4]triazolo[4,3-a]pyridine sulfonamides as potential antimalarial agents: In silico studies, synthesis and in vitro evaluation
Karpina, Veronika R.,Kovalenko, Svitlana S.,Kovalenko, Sergiy M.,Drushlyak, Oleksandr G.,Bunyatyan, Natalya D.,Georgiyants, Victoriya A.,Ivanov, Vladimir V.,Langer, Thierry,Maes, Louis
, (2020/10/18)
For the development of new and potent antimalarial drugs, we designed the virtual library with three points of randomization of novel [1,2,4]triazolo[4,3-a]pyridines bearing a sulfonamide fragment. The library of 1561 compounds has been investigated by both virtual screening and molecular docking methods using falcipain-2 as a target enzyme. 25 chosen hits were synthesized and evaluated for their antimalarial activity in vitro against Plasmodium falciparum. 3-Ethyl-N-(3-fluorobenzyl)-N-(4-methoxyphenyl)-[1,2,4]triazolo[4,3-a]pyridine-6-sulfonamide and 2-(3-chlorobenzyl)-8-(piperidin-1-ylsulfonyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one showed in vitro good antimalarial activity with inhibitory concentration IC50 = 2.24 and 4.98 μM, respectively. This new series of compounds may serve as a starting point for future antimalarial drug discovery programs.
Compounds for the Treatment of Hepatitis C
-
Page/Page column 33, (2009/03/07)
The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
