60598-02-9

Upstream product

• 60598-03-0 13,18-dioxa-1,4,7,10-tetraazabicyclo[8.5.5]eicosane 
• 39678-05-2 3,6-ditosyl-3,6-diazaoctanedioyl dichloride 
• 52601-77-1 4,10-bis(p-tolylsulphonyl)-1,7-dioxa-4,10-diazacyclododecane 
• 294-92-8 diaza[12]crown-4 
• 6315-52-2 1,2-bis-tosyloxyethane 
• 118074-98-9 4,10-bis<2-(p-tolylsulphonylamino)ethyl>-1,7-dioxa-4,10-diazacyclododecane 
• 60598-01-8 4,7-bis-(toluene-4-sulfonyl)-13,18-dioxa-1,4,7,10-tetraaza-bicyclo[8.5.5]eicosane-2,9-dione 

Relevant academic research and scientific papers

MACROHETEROCYCLES XLVIII. SYNTHESIS OF POLYAZAOXACRYPTANDS IN A TWO-PHASE SYSTEM

A method is proposed for the production of polyazaoxacryptands by the condensation of N,N'-bis(tosylaminoethyl)diazacrown ethers with ditosyloxy derivatives or dibromides in the toluene-45percent aqueous sodium hydroxide two-phase system.The catalytic act

MACROHETEROCYCLES. PART 44. FACILE SYNTHESIS OF AZACROWN ETHERS AND CRYPTANDS IN A TWO-PHASE SYSTEM

A facile procedure is proposed for the preparation of azacrown ethers and cryptands by condensation of dibromides or ethylene glycol bis(toluene-p-sulphonate)s with acyclic bis(sulphonamide)s or with bisdiazacrown ethers, respectively.The reaction was carried out in a two-phase system of aqueous alkali-toluene (benzene)in the presence of quaternary ammonium salts as phase transfer catalysts.The catalytic activity decreased in the sequence: Bu4NI ca.Bu4NBr > Bu4NCl > Bu4NHSO4 > Et3NCH2C6H5NCl.Maximum yields of twelve-membered azacrown ethers are obtained when lithium hydroxide is used, while crown ethers of larger size are observed in the presence of sodium or potassium hydroxides; this may be due to a template effect.

Complexes of macrocyclic compounds

Novel macrocyclic (monocyclic and bicyclic) compounds having nitrogen bridgehead atoms and having in the hydrocarbon bridging chains at least two additional hetero atoms selected from the group consisting of sulfur, oxygen, and nitrogen, when admixed with a compatible cation-donor compound form stable cation-containing macrocyclic complexes which, in turn, can be conveniently dissociated by addition of acid or a quaternizing agent. The novel macrocyclics are valuable for use in the same way and for the same purposes as chelating agents.

Monocyclic macrocyclic compounds and complexes thereof

Novel monocyclic macrocyclic compounds having nitrogen bridgehead atoms and having in the hydrocarbon bridging chains at least two additional hetero atoms selected from the group consisting of sulfur, oxygen, and nitrogen, when admixed with a compatible cation-donor compound form stable cation-containing macrocyclic complexes which, in turn, can be conveniently dissociated by addition of acid or a quaternizing agent. The novel macrocyclics are valuable for use in the same way and for the same purposes as chelating agents.