118074-98-9

Upstream product

• 52601-77-1 4,10-bis(p-tolylsulphonyl)-1,7-dioxa-4,10-diazacyclododecane 
• 3634-89-7 N-(p-toluenesulfonyl)aziridine 
• 294-92-8 diaza[12]crown-4 

Downstream Products

• 132111-83-2 4,7,10-tritosyl-16,19-dioxa-1,4,7,10,13-pentaazabicyclo<11.5.5>tricosane 
• 121031-84-3 4,9-bis(p-tolylsulphonyl)benz-15,20-dioxa-1,4,9,12-tetra-azabicyclo<10.5.5>docosane 
• 118074-99-0 4,10-bis(p-tolylsulphonyl)-7,16,21-trioxa-1,4,10,13-tetra-azabicyclo<11.5.5>tricosane 
• 121057-92-9 4,11-bis(p-tolylsulphonyl)-6,9-etheno-17,22-dioxa-1,4,11,14-tetra-azabicyclo<12.5.5>tetracosa-6,8-diene 
• 60598-02-9 4,7-bis(p-tolylsulphonyl)-13,18-dioxa-1,4,7,10-tetra-azabicyclo<8,5,5>icosane 
• 118075-00-6 4,13-bis(p-tolylsulphonyl)-7,10,19,24-tetraoxa-1,4,13,16-tetra-azabicyclo<14.5.5>hexacosane 

Relevant academic research and scientific papers

MACROHETEROCYCLES XLVIII. SYNTHESIS OF POLYAZAOXACRYPTANDS IN A TWO-PHASE SYSTEM

A method is proposed for the production of polyazaoxacryptands by the condensation of N,N'-bis(tosylaminoethyl)diazacrown ethers with ditosyloxy derivatives or dibromides in the toluene-45percent aqueous sodium hydroxide two-phase system.The catalytic act

MACROHETEROCYCLES. PART 44. FACILE SYNTHESIS OF AZACROWN ETHERS AND CRYPTANDS IN A TWO-PHASE SYSTEM

A facile procedure is proposed for the preparation of azacrown ethers and cryptands by condensation of dibromides or ethylene glycol bis(toluene-p-sulphonate)s with acyclic bis(sulphonamide)s or with bisdiazacrown ethers, respectively.The reaction was carried out in a two-phase system of aqueous alkali-toluene (benzene)in the presence of quaternary ammonium salts as phase transfer catalysts.The catalytic activity decreased in the sequence: Bu4NI ca.Bu4NBr > Bu4NCl > Bu4NHSO4 > Et3NCH2C6H5NCl.Maximum yields of twelve-membered azacrown ethers are obtained when lithium hydroxide is used, while crown ethers of larger size are observed in the presence of sodium or potassium hydroxides; this may be due to a template effect.

Macroheterocycles; XXXIX. A Convenient Synthesis of Polyaza-oxa Cryptands

A convenient procedure is proposed for the synthesis of cryptands by the alkylation of bis-N-(2-tosylaminoethyl)diaza-crown ethers with dibromides in the two-phase system: aqueous sodium hydroxide/toluene.