606080-38-0

Usage

Structure

A derivative of benzene with a fluorine and iodine atoms attached to the ring, and an azidomethyl group attached to a carbon atom.

Functional groups

Azidomethyl, Fluoro, Iodo

Organic synthesis

Used as a building block for the synthesis of various complex organic molecules.

Pharmaceutical applications

Potential use in the development of pharmaceutical compounds.

Azide-alkyne cycloaddition

The azide group allows for this reaction, which is widely used in the synthesis of organic compounds.

Cross-coupling reactions

The fluoro and iodo substituents make the compound suitable for these reactions.

Functionalization reactions

The presence of fluoro and iodo groups enables various functionalization reactions in organic chemistry.

Upstream product

• 70931-59-8 1-(bromomethyl)-4-fluoro-2-iodobenzene 

Relevant academic research and scientific papers

HIV integrase inhibitors

The invention encompasses a series bicyclic pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.

HIV INTEGRASE INHIBITORS

The invention encompasses a series bicyclic pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.

BICYCLIC HETEROCYCLES AS HIV INTEGRASE INHIBITORS

The invention encompasses a series cyclic bicyclic pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.