70931-59-8

Usage

Uses

Used in Pharmaceutical Industry:
1-BROMOMETHYL-4-FLUORO-2-IODO-BENZENE is used as a building block in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs with potential therapeutic effects. Its unique structure and functional groups allow for the creation of diverse chemical entities that can be further modified to enhance their biological activity and pharmacological properties.
Used in Agrochemical Industry:
1-BROMOMETHYL-4-FLUORO-2-IODO-BENZENE is used as a starting material in the synthesis of agrochemicals, such as pesticides and herbicides, due to its potential to form new compounds with effective pesticidal or herbicidal properties. Its unique structure and functional groups can be utilized to design and develop novel agrochemicals that can address specific agricultural challenges.
Used in Organic Synthesis:
1-BROMOMETHYL-4-FLUORO-2-IODO-BENZENE is used as a versatile intermediate in organic synthesis for the preparation of various chemical compounds with potential applications in different industries. Its unique structure and functional groups make it a valuable precursor for the synthesis of complex organic molecules, which can be further modified to achieve desired properties and functionalities.
It is important to handle 1-BROMOMETHYL-4-FLUORO-2-IODO-BENZENE with care and use appropriate safety measures during its synthesis and application processes, as it can be hazardous if not handled properly.

Upstream product

• 56096-89-0 4-fluoro-2-iodobenzoic acid 
• 367-29-3 3-fluoro-6-methylaniline 
• 446-10-6 2-nitro-4-fluorotoluene 
• 13194-67-7 4-fluoro-2-iodotoluene 

Downstream Products

• 606080-38-0 1-(azidomethyl)-4-fluoro-2-iodobenzene 
• 1401971-06-9 4-fluoro-2-iodo-1-(methoxymethyl)benzene 
• 1188513-89-4 1-chloromethyl-4-fluoro-2-iodo-benzene 
• 1092716-84-1 ((5-fluoro-2-(methoxymethyl)phenyl)ethynyl)trimethylsilane 
• 1394351-61-1 C₂₁H₂₀F₂I₂O₄ 
• 1394351-63-3 C₁₆H₁₂F₂I₂O₂ 
• 1394350-78-7 ethyl 2-(4-fluoro-2-iodobenzyl)-2-amino-3-(4-fluoro-2-iodophenyl)propanoate 

Relevant academic research and scientific papers

Access to chiral tetrahydrofluorenes through a palladium-catalyzed enantioselective tandem intramolecular Heck/Tsuji-Trost reaction

A palladium-catalyzed enantioselective coupling of 2,5-cyclohexadienyl-substituted aryl iodides and carbon or heteroatom nucleophiles is described. The reaction proceeded via a tandem asymmetric Heck insertion and Tsuji-Trost allylation, enabling the rapi

Stereoretentive Intramolecular Glycosyl Cross-Coupling: Development, Scope, and Kinetic Isotope Effect Study

A series of cyclic C-glycosides were synthesized using the palladium-catalyzed stereoretentive intramolecular glycosylation of aryl iodides by employing a bulky phosphine ligand. A variety of functional groups are tolerated in the reaction, and enantioenr

A concise synthesis of chiral indanes as α1A adrenoceptor partial agonists

The synthesis of a series of chiral indanes with reported α1A partial agonist activity is outlined, applying a rhodium catalysed cyclisation for template construction. This method was extended to the asymmetric synthesis of lead compound PF-037

Preparation of polyfunctional indazoles and heteroarylazo compounds using highly functionalized zinc reagents

Readily available 2-chloromethylarylzinc reagents react with functionalized aryldiazonlum tetrafluoroborates providing polyfunctional indazoles. Selective metalations of these 2-aryl-2H-indazoles afford new polycyclic aromatlcs. The performance of a chemo

Novel 2-imidazoles as potent, selective and CNS penetrant α1A adrenoceptor partial agonists

A novel series of central nervous system (CNS) penetrant indane 2-imidazoles have been identified as potent, partial agonists of the α1A adrenergic receptor, having good selectivity over the α1B, α1D and α2 sub-

A potent and orally active HIV-1 integrase inhibitor

A 1,6-naphthyridine inhibitor of HIV-1 integrase has been discovered with excellent inhibitory activity in cells, good pharmacokinetics, and an excellent ability to inhibit virus with mutant enzyme.

3 Fluoro-10-piperazino-8-substituted 10,11-dihydrodibenzo-(bf) thiepins and method for the preparation thereof

Techniques for the preparation of 3-fluoro-10-piperazino-8-substituted 10,11-dihydrodibenzo-(b,f) thiepins and their addition salts with organic and inorganic acids are disclosed. The described compositions evidence psychotropic activity and low toxicity and are characterized as neuroliptics with a high degree of cataleptic, anti-apomorphine and central depressant action.