6065-72-1Relevant academic research and scientific papers
Kinetics and mechanism of oxidation of aliphatic acetals with peroxomonosulphate
Janakiram,Venkataraman,Basheer Ahamed
, p. 339 - 341 (2007/10/03)
The oxidation of fifteen aliphatic acetals of normal aliphatic aldehydes and substituted aliphatic aldehydes with aliphatic and substituted aliphatic as well as with aromatic alcohols by peroxomonosulphate in aqueous acetic acid medium is first order each in [oxidant] and [acetal] and yields the corresponding esters as the main product. The oxidation reaction is independent of change in dielectric constant of the medium. The activation enthalpies and entropies of the reactions are linearly related. A mechanism involving hydride ion shift is proposed.
The enantiomer ratio strongly depends on the alkyl part of the acyl donor in transesterification with lipase B from Candida antarctica
Hoff, Bard H.,Anthonsen, Henrik W.,Anthonsen, Thorleif
, p. 3187 - 3192 (2007/10/03)
Three secondary alcohols, 1-phenoxy-, 1-phenylmethoxy- and 1-(2-phenylethoxy)-2-propanol, have been resolved by transesterification with the acyl donors 2-chloroethyl butanoate, 2,2,2-trichloroethyl butanoate, vinyl butanoate and butanoic anhydride using lipase B from Candida antarctica as catalyst in hexane. The enantiomer rate E, which was calculated on the basis of a ping-pong bi-bi mechanism, was highest when 2-chloroethyl butanoate was used as acyl donor, however the reaction was reversible. It was shown that the E-value increased when the amount of 2,2,2-trichloroethyl butanoate was reduced. It is also indicated that butanoic anhydride and vinyl butanoate make the lipase less specific probably by acylation. Copyright (C) Elsevier Science Ltd.
