60656-04-4

Usage

Class

Indazoles

Structural feature

Phenyl group attached to the indazole ring structure

Usage

Medicinal chemistry for the development of potential pharmaceutical drugs

Biological activities

Anticancer, antifungal, and antiviral properties

Importance

Promising molecule for further research and development in the pharmaceutical industry due to its unique structure and diverse biological activities.

InChI:InChI=1/C17H14N2/c1-2-7-15(8-3-1)19-17-14(12-18-19)11-10-13-6-4-5-9-16(13)17/h1-9,12H,10-11H2

Upstream product

• 60656-32-8 1-phenyl-4,5-dihydro-1H-benzo[g]indazole-3-carboxylic acid 
• 50493-08-8 2-formyl-1-tetralone 
• 64-17-5 ethanol 
• 100-63-0 phenylhydrazine 
• 117582-62-4 1-bromo-2-formyl-3,4-dihydronaphthalene 
• 59-88-1 phenylhydrazine hydrochloride 
• 871110-19-9 3-(methylthio)-1-phenyl-4,5-dihydro-1H-benzo[g]indazole 
• 40685-04-9 1,2,3,4-tetrahydro-2-(hydroxymethylene)naphthalen-1-one 

Relevant academic research and scientific papers

Palladium-catalyzed C-N bond formation: synthesis of 1-aryl-1H-pyrazoles from β-bromovinyl aldehydes and arylhydrazines

Cyclic and acyclic β-bromovinyl aldehydes are cyclized with an array of arylhydrazines in toluene at 125 °C in the presence of a palladium catalyst and a phosphorus chelating ligand together with NaOtBu to give 1-aryl-1H-pyrazoles in moderate t

Regioselective synthesis of 1-aryl-3,4-substituted/annulated-5-(methylthio) pyrazoles and 1-aryl-3-(methylthio)-4,5-substituted/annulated pyrazoles

Highly efficient and regioselective synthesis of 1-aryl-3,4-substituted/ annulated-5-(methylthio)-pyrazoles and 1-aryl-3-(methylthio)-4,5-substituted/ annulated pyrazoles has been reported via cyclocondensation of arylhydrazines with either α-oxoketene dithioacetals or β-oxodithioesters.