60664-00-8

Basic information

• Product Name: 6-AMINO-1-(4-CHLORO-PHENYL)-1H-PYRIMIDINE-2,4-DIONE
• Synonyms: IFLAB-BB F1967-0019;AKOS B034890;AKOS BC-1296;6-AMINO-1-(4-CHLORO-PHENYL)-1H-PYRIMIDINE-2,4-DIONE;6-AMINO-1-(4-CHLOROPHENYL)PYRIMIDINE-2,4(1H,3H)-DIONE;SPECS AR-434/42804637
• CAS NO: 60664-00-8
• Molecular Formula: C₁₀H₈ClN₃O₂
• Molecular Weight: 237.64
• Mol File: 60664-00-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6-AMINO-1-(4-CHLORO-PHENYL)-1H-PYRIMIDINE-2,4-DIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-AMINO-1-(4-CHLORO-PHENYL)-1H-PYRIMIDINE-2,4-DIONE(60664-00-8)
• EPA Substance Registry System: 6-AMINO-1-(4-CHLORO-PHENYL)-1H-PYRIMIDINE-2,4-DIONE(60664-00-8)

Safety Data

• Hazardous Substances Data: 60664-00-8(Hazardous Substances Data)

Upstream product

• 16837-11-9 6-amino-1-(4-chloro-phenyl)-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one 
• 105-56-6 ethyl 2-cyanoacetate 
• 140-38-5 N-(4-chlorophenyl)urea 
• 3696-23-9 N-(4-chlorophenyl)thiourea 

Downstream Products

• 634170-94-8 N-{1-(4-chlorophenyl)-5-trifluoromethyl-2,4,6-trioxo-2,3,4,5,6,7-hexahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl}benzenesulfonamide 

Relevant articles and documents

Reactions of nitriles under acidic conditions : Part IX - Synthesis of 6-amino-1-aryluracils, 6-amino-1-aryl-2-thiouracils and 6-amino-1,3-diaryl-2-thiouracils under acidic conditions

6-Amino-1-aryluracils (11a-g), 6-amino-1-aryl-2-thiouracils (12a-g), and 6-amino-1,3-diaryl-2-thiouracils (6a,b) have been synthesised through the dry hydrogen chloride gas-catalysed condensation of ethyl cyanoacetate (7) with appropriate arylureas and thioureas. 1-Aryl (12a-g) and 1,3-diaryl-2-thiouracils (6c-g) have been converted to the corresponding 1-aryl (15a-g) and novel hitherto unre-ported, 1,3-diaryluracils (5a-e) through their oxidative desulphurisation.