60669-42-3Relevant academic research and scientific papers
Catalytic, oxidant-free, direct olefination of alcohols using Wittig reagents
Khaskin,Milstein
supporting information, p. 9002 - 9005 (2015/05/27)
Reported here is the catalytic, acceptorless coupling of alcohols with in situ generated, non-stabilized phosphonium ylides to form olefins as major products. The reaction uses low catalyst loadings and does not require added oxidants. Hydrogenation of the product is minimized and the reaction leads to Z (aliphatic) or E (benzylic) stereospecificity.
Simple protocol for enhanced (E)-selectivity in Julia-Kocienski reaction
Pospí?il, Ji?í
supporting information; experimental part, p. 2348 - 2352 (2011/05/16)
A short and efficient Julia-Kocienski olefination protocol, based upon the use of chelating agents (18-crown-6 or TDA-1 for K+; 12-crown-4 or HMPA for Li+), was developed. This protocol enhances the (E)-selectivity of the reaction an
DBP YLDES: WITTIG REAGENTS FOR SYNTHESIS OF E-ALKENES FROM ALDEHYDES
Vedejs, E.,Marth, C.
, p. 3445 - 3448 (2007/10/02)
Phosphorus yldes based on the dibenzophosphole (DPP) ring system convert aldehydes into trans-disubstituted oxaphosphetanes with good to excellent selectivity.Decomposition at 70-110 deg C affords alkenes with E:Z rations from 6:1 to > 100:1.
