60692-40-2Relevant academic research and scientific papers
Domino Ring-Opening of N-Tosyl Vinylaziridines Triggered by Aryne Diels-Alder Reaction
Liu, Jiupeng,Li, Jiaqi,Ren, Bowen,Zhang, Yun,Xue, Linyi,Wang, Yanying,Zhao, Jingjing,Zhang, Puyu,Xu, Xuejun,Li, Pan
supporting information, p. 4734 - 4739 (2021/09/14)
The reactivity of N-tosyl vinylaziridines toward arynes has been demonstrated under mild and transition-metal-free conditions to yield 2-(phenanthren-9-yl)ethan-1-sulfamides in moderate to good yields. The selective synthesis of N-H and N-aryl products was accomplished using CsF in MeCN and KF/18-C-6 in 1,4-dioxane, respectively. This cascade process involves a sequential Diels-Alder reaction, ring-opening aromatization, ene-reaction, and selective N-arylation reaction. (Figure presented.).
Metal-free aza-Claisen type ring expansion of vinyl aziridines: An expeditious synthesis of seven membered N-heterocycles
Singh, Deepak,Ha, Hyun-Joon
, p. 3093 - 3097 (2019/03/26)
A metal-free approach for the synthesis of 7-membered aza-heterocycles has been developed by the intermolecular [5 + 2] cycloaddition of non-activated vinylaziridines and alkynes. This method has a broad substrate scope under mild reaction conditions to a
