606949-09-1

Basic information

• Product Name: (2S,3S)-3-Phenyl-2-(2,2,2-trifluoro-acetylamino)-hex-5-enoic acid methyl ester
• CAS NO: 606949-09-1
• Molecular Weight: 315.292
• Mol File: 606949-09-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,3S)-3-Phenyl-2-(2,2,2-trifluoro-acetylamino)-hex-5-enoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S)-3-Phenyl-2-(2,2,2-trifluoro-acetylamino)-hex-5-enoic acid methyl ester(606949-09-1)
• EPA Substance Registry System: (2S,3S)-3-Phenyl-2-(2,2,2-trifluoro-acetylamino)-hex-5-enoic acid methyl ester(606949-09-1)

Safety Data

• Hazardous Substances Data: 606949-09-1(Hazardous Substances Data)

Upstream product

• 606948-99-6 (2S,3S)-2-amino-3-phenyl-5-hexenoic acid 
• 186581-53-3 diazomethane 
• 606949-13-7 (2S,3S)-3-Phenyl-2-(2,2,2-trifluoro-acetylamino)-hex-5-enoic acid 

Relevant articles and documents

Synthesis of β-phenyl-δ,ε-unsaturated amino acids and stereoselective introduction of side chain groups into [4,3,0]-bicyclic β-turn dipeptides

(2S,3S)- and (2R,3R)-2-amino-3-phenyl-5-hexenoic acids have been synthesized in large scale by using Ni(II)-complexes as a template. The amino acids were used in the synthesis of [4,3,0]-bicyclic β-turn mimetics by a convergent methodology. The unique advantage of this strategy is the convenience of introducing side chain groups with predetermined chiralities on both the five- and six-membered heterocyclic rings.