60696-83-5

Basic information

• Product Name: Ethanol, 2-(2-methoxyethoxy)-, methanesulfonate
• CAS NO: 60696-83-5
• Molecular Formula: C6H14O5S
• Molecular Weight: 198.24
• Mol File: 60696-83-5.mol

Chemical Properties

• CAS DataBase Reference: Ethanol, 2-(2-methoxyethoxy)-, methanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanol, 2-(2-methoxyethoxy)-, methanesulfonate(60696-83-5)
• EPA Substance Registry System: Ethanol, 2-(2-methoxyethoxy)-, methanesulfonate(60696-83-5)

Safety Data

• Hazardous Substances Data: 60696-83-5(Hazardous Substances Data)

Upstream product

• 111-77-3 2-(2-methoxyethoxy)ethyl alcohol 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 114185-63-6 2-iodo-5-<2-(2-methoxyethoxy)ethoxy>benzoic acid 
• 23778-52-1 3,6,9,12,15-pentaoxahexadecanol 
• 31576-51-9 2-(2-methoxyethoxy)ethanamine 
• 215181-61-6 1-(1-ethoxy-2-azido)-2-methoxyethane 
• 1407968-89-1 3-{5-tert-butyl-2-[2-(2-methoxyethoxy)ethoxy]benzyl}-5-tert-butyl-2-[2-(2-methoxyethoxy)]benzaldehyde 
• 1174295-64-7 C₁₅H₂₄O₃ 
• 1407968-90-4 1,3-bis-{5-tert-Butyl-2-[2-(2-methoxyethoxy)ethoxy]benzyl}-5-tert-butyl-2-[2-(2-methoxyethoxy)ethoxy]benzene 
• 1407968-87-9 2-bromo-4-tert-butyl-1-[2-(2-methoxyethoxy)ethoxy]benzene 
• 1118566-54-3 (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-(2-(2-methoxyethoxy)ethoxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 
• 1118566-55-4 (2R,3R,4R,5S,6R)-2-(4-chloro-3-(4-(2-(2-methoxyethoxy)ethoxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 
• 114185-64-7 2-iodosyl-5-<2-(2-methoxyethoxy)ethoxy>benzoic acid 
• 265976-77-0 (3,5-bis-{3,5-bis-[2-(2-methoxy-ethoxy)-ethoxy]-benzyloxy}-phenyl)-methanol 
• 265976-76-9 3,5-bis-{3,5-bis-[2-(2-methoxy-ethoxy)-ethoxy]-benzyloxy}-benzoic acid methyl ester 
• 225917-52-2 C₄₁H₅₉BrO₁₄ 

Relevant articles and documents

Thermomorphic phase separation in ionic liquid-organic liquid systems - Conductivity and spectroscopic characterization

Electrical conductivity, FT-Raman and NMR measurements are demonstrated as useful tools to probe and determine phase behavior of thermomorphic ionic liquid-organic liquid systems. To illustrate the methods, consecutive conductivity measurements of a thermomorphic methoxyethoxyethyl-imidazolium ionic liquid/ 1-hexanol system are performed in the temperature interval 25-80°C using a specially constructed double-electrode cell. In addition. FT-Raman and 1H-NMR spectroscopic studies performed on the phase-separable system in the same temperature interval confirm the mutual solubility of the components in the system, the liquid liquid equilibrium phase diagram of the binary mixture, and signify the importance of hydrogen bonding between the ionic liquid and the hydroxyl group of the alcohol. The Owner Societies 2005.

PYRAZOLOTRIAZOLOPYRIMIDINE DERIVATIVES AS A2A RECEPTOR ANTAGONIST

Disclosed herein is a pyrazolotriazolopyrimidine derivative or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof useful as A2A receptor antagonist, and a pharmaceutical composition comprising the same. Also disclosed herein is a method of treating cancer using the pyrazolotriazolopyrimidine derivative or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof as A2A receptor antagonist.

2-PHENYLIMIDAZO[4,5-B]PYRIDIN-7-AMINE DERIVATES USEFUL AS INHIBITORS OF MAMMALIAN TYROSINE KINASE ROR1 ACTIVITY

Compound of formula (I′) or (I′′) or a pharmaceutically acceptable salt thereof. The compound is an inhibitor of mammalian kinase enzyme activity, including ROR1 tyrosine kinase activity and may be used in the treatment of disorders associated with such activity.

Lipase-catalyzed synthesis of sucrose monolaurate and its antibacterial property and mode of action against four pathogenic bacteria

The aim of this work was to evaluate the antibacterial activities and mode of action of sucrose monolaurate (SML) with a desirable purity, synthesized by Lipozyme TL IM-mediated transesterification in the novel ionic liquid, against four pathogenic bacteria including L. monocytogenes, B. subtilis, S. aureus, and E. coli. The antibacterial activity was determined by minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and the time–kill assay. SML showed varying antibacterial activity against tested bacteria with MICs and MBCs of 2.5 and 20 mM for L. monocytogenes, 2.5 and 20 mM for B. subtilis, 10 and 40 mM for S. aureus, respectively. No dramatic inhibition was observed for E. coli at 80 mM SML. Mechanism of bacterial inactivation caused by SML was revealed through comprehensive factors including cell morphology, cellular lysis, membrane permeability, K+ leakage, zeta potential, intracellular enzyme, and DNA assay. Results demonstrated that bacterial inactivation against Gram-positive bacteria was primarily induced by the pronounced damage to the cell membrane integrity. SML may interact with cytoplasmic membrane to disturb the regulation system of peptidoglycan hydrolase activities to degrade the peptidoglycan layer and form a hole in the layer. Then, the inside cytoplasmic membrane was blown out due to turgor pressure and the cytoplasmic materials inside leaked out. Leakage of intracellular enzyme to the supernatants implied that the cell membrane permeability was compromised. Consequently, the release of K+ from the cytosol lead to the alterations of the zeta potential of cells, which would disturb the subcellular localization of some proteins, and thereby causing bacterial inactivation. Moreover, remarkable interaction with DNA was also observed. SML at sub-MIC inhibited biofilm formation by these bacteria.

SILICON PHTHALOCYANINE COMPLEX, PREPARATION METHOD AND MEDICINAL APPLICATION THEREOF

The present invention relates to a silicon phthalocyanine complex, the preparation method and the medicinal application thereof. The present invention particularly relates to a silicon phthalocyanine complex of formula (I), the preparation method thereof and a pharmaceutical composition comprising the same, as well as the use thereof as a photosensitizer, in particular the use in the treatment of cancers, wherein each substituent in formula (I) is the same as defined in the description.

Design, synthesis and cytotoxic activity of water-soluble quinones with dibromo-p-benzoquinone cores and amino oligo(ethylene glycol) side chains against MCF-7 breast cancer cells

A series of novel quinones was synthesized by reacting tetrabromo-p-benzoquinone with amino oligo(ethylene glycol) dendrons of generation numbers g = 0-2. According to the performed shake-flask experiments, their aqueous solubility (S = 18 mg l?1-1.6 g ml?1) and partition coefficients (log?Poct/wat = 2.53-0.21) can be tuned in a wide range as a function of g. In vitro cytotoxicity assays of tetrabromo-p-benzoquinone and its derivatives against MCF-7 human breast cancer cells showed a concentration- and generation-specific biological activity with IC50-values as low as 0.8 μM. Further investigations revealed a considerable selectivity against cancer cells, as indicated by a weak cytotoxicity against human skin fibroblast cells (>80% survival) within the studied range of concentrations. The results demonstrate that these novel amino oligo(ethylene glycol) dendrons depict versatile tools to ameliorate physical and pharmacological characteristics of extremely hydrophobic molecules and make them susceptible to biological applications.

Self-Assembly Can Direct Dynamic Covalent Bond Formation toward Diversity or Specificity

With the advent of reversible covalent chemistry the study of the interplay between covalent bond formation and noncovalent interactions has become increasingly relevant. Here we report that the interplay between reversible disulfide chemistry and self-assembly can give rise either to molecular diversity, i.e., the emergence of a unprecedentedly large range of macrocycles or to molecular specificity, i.e., the autocatalytic emergence of a single species. The two phenomena are the result of two different modes of self-assembly, demonstrating that control over self-assembly pathways can enable control over covalent bond formation.

IONIC LIQUID SYSTEMS

The present invention relates to an ionic liquid system for enhanced delivery and/or deposition of a perfume raw material onto a substrate, particularly fabric, hard surfaces, soft surfaces, skin, or hair. The invention also relates to consumer products comprising the new ionic liquid systems, and processes for making and methods of using such ionic liquid systems and consumer products.

Ether-based bis-imidazole ionic liquid used for absorbing SO2, preparation method and application method thereof

The invention relates to ether-based bis-imidazole ionic liquid used for absorbing SO2. The ether-based bis-imidazole ionic liquid has the advantages of high absorption capacity, good stability and recyclable performance, no secondary pollution is generated during a desulphurization process, usage of the ether-based bis-imidazole ionic liquid for desulphurization is a technical method having industrial application potential for high-efficiency removal of SO2. According to a preparation method, process is simple, stability of the preparation process is high, and repeatability is good.

FRAGRANCE COMPOSITIONS COMPRISING IONIC LIQUIDS

The present invention relates to a fragrance composition comprising ionic liquids for enhanced evaporation of the perfume raw materials. The invention also relates to methods of use of the fragrance compositions for perfuming suitable substrates, particularly skin and hair.