606971-75-9Relevant academic research and scientific papers
Design, synthesis, and evaluation of novel 2-substituted-4-aryl-6,7,8,9- tetrahydro-5H-pyrimido[4,5-b][1,5]oxazocin-5-ones as NK1 antagonists
Seto, Shigeki,Tanioka, Asao,Ikeda, Makoto,Izawa, Shigeru
, p. 5717 - 5732 (2007/10/03)
A series of novel bicyclic pyrimidine derivatives was prepared as part of a search for NK1 antagonist aimed at the treatment of urinary incontinence. Among them, 3g, a pyrimido[4,5-b][1,5]oxazocine derivative, bearing a 4-acetylpiperazinyl grou
FUSED BICYCLIC PYRIMIDINE DERIVATIVES
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Page 25, (2010/02/10)
A novel fused bicyclic pyrimidine derivative or a salt thereof that acts as a tachykinin receptor antagonist and, in particular, as an NK1 receptor antagonist is represented by the following general formula (1): wherein the rings A and B are each a benzen
