6071-21-2Relevant academic research and scientific papers
A short and efficient synthesis of the polyacetylene natural product deca-4,6,8-triyn-1-ol
Machado, Vanessa Rocha,Biavatti, Maique Weber,Danheiser, Rick L.
, p. 3405 - 3408 (2018/08/21)
A practical and efficient four-step synthesis of the natural product deca-4,6,8-triyn-1-ol has been achieved beginning with (triisopropylsilyl)acetylene. This trialkyne has potential utility as a key intermediate for the total synthesis of the antitumor butenolide natural product vernoniyne.
Synthesis and stability of a homologous series of triynol natural products and their analogues
Luu, Thanh,Tykwinski, Rik R.
, p. 8982 - 8985 (2007/10/03)
A series of polyyne natural products 1, 13, and 31 and analogues 14, 21, and 22 are synthesized in six steps. The key step is a Fritsch-Buttenberg- Wiechell rearrangement in which a triyne framework is formed from the appropriate dibromoolefin precursor.
