624-66-8

Basic information

• Product Name: 1-PROPYN-1-YL IODIDE
• Synonyms: propynyliodide;1-IODO-1-PROPYNE;1-PROPYN-1-YL IODIDE;1-Propynyl iodide;1-iodoprop-1-yne
• CAS NO: 624-66-8
• Molecular Formula: C₃H₃I
• Molecular Weight: 165.96
• Product Categories: Acetylenes;Diyne Compounds (LB Films);Functional Materials;Functionalized Acetylenes;LB Films
• Mol File: 624-66-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 110 °C
• Flash Point: 39.1°C
• Appearance: /
• Density: 1,99 g/cm3
• Vapor Pressure: 28.4mmHg at 25°C
• Refractive Index: 1.5430 to 1.5500
• Storage Temp.: Refrigerator
• CAS DataBase Reference: 1-PROPYN-1-YL IODIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-PROPYN-1-YL IODIDE(624-66-8)
• EPA Substance Registry System: 1-PROPYN-1-YL IODIDE(624-66-8)

Safety Data

• Statements: 10
• Safety Statements: 16
• RIDADR: 1993
• HazardClass: 3
• PackingGroup: III
• Hazardous Substances Data: 624-66-8(Hazardous Substances Data)

Usage

General Description

1-Propyn-1-yl iodide, also known as propargyl iodide or 3-iodopropyne, is a chemical compound with the molecular formula C3H3I. It is an organoiodine compound used as a building block in organic synthesis, specifically in the preparation of alkynes and alkenes. The compound is clear yellow to brown liquid with a pungent odor, which should be handled carefully due to its toxic, corrosive and potentially harmful effects. Moreover, 1-propyn-1-yl iodide is sensitive to light, heat, and moisture, thus it needs to be stored in a cool, dry, and well-ventilated place away from ignition sources and strong oxidizing agents. It is important to wear appropriate personal protection when handling this chemical.

InChI:InChI=1/C3H3I/c1-2-3-4/h1H3

Upstream product

• 53210-70-1 silver(I) propynyde 
• 590-14-7 1-bromo-1-propene 
• 7553-56-2 iodine 
• 857233-25-1 1,1,2-triiodo-propene 
• 74-99-7 prop-1-yne 
• 107-19-7 propargyl alcohol 
• 16466-97-0 1-propynylmagnesium bromide 
• 6224-91-5 trimethyl(prop-1-ynyl)silane 

Downstream Products

• 562835-23-8 (2E,3R,4R,5R)-4-benzoyloxy-2-(2,4-hexadiynylidene)-1,6-dioxaspiro[4.5]decan-3-ol 
• 74-99-7 prop-1-yne 
• 520-74-1 capillene 
• 7796-36-3 cis-1-Jod-prop-1-en 
• 6104-36-5 1-(triphenylsilyl)prop-1-yne 
• 6071-21-2 deca-4,6,8-triyn-1-ol 
• 1615211-71-6 3-(2-chloro-6-ethyl-4-prop-1-ynylphenyl)-4-methoxybicyclo[3.2.1 ]oct-3-en-2-one 

Relevant articles and documents

Synthesis of stereoisomers of artemisia and chrysanthemum bis(acetylenic) enol ether spiroacetals

An 11-step synthesis is described of two diastereomeric candidates for a bis(acetylenic) enol ether spiroacetal isolated from Chrysanthemum boreale. Key steps in the synthetic route include spiroacetal lactone alkylidenation and subseqent modified Cadiota-Chodkiewicz cross-coupling to install the bis(acetylenic) enol ether functionality. From NMR comparisons, neither of the candidates, whose structures were confirmed by single-crystal X-ray diffraction, correspond to the natural product, and a proposal for the correct structure is put forward.

Synthesis of 1-iodopropyne

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