60723-28-6Relevant academic research and scientific papers
Catalytic Asymmetrization of meso-3,7-Bis-siloxycycloheptene by Chiral Rhodium(I)-binap Catalyst: the Enantiocontrolled Asymmetric Synthesis of (-)-(S)-Physoperuvine
Hiroya, Kou,Ogasawara, Kunio
, p. 2205 - 2206 (2007/10/02)
Catalytic asymmetrization of meso-3,7-bis-tert-butyldimethylsiloxycycloheptene occurs in the presence of a chiral rhodium(I) binap catalyst to give optically active 4-tert-butyldimethylsiloxycycloheptanone in 70percent ee after hydrolytic workup, the (R)-enantiomer of which has been transformed into (-)-(S)-physoperuvine, the major alkaloid of Physalis peruviana.
Oxygenation of N-Cyclohepthylbenzamides with Beauveria sulfurescens
Johnson, Roy A.,Herr, Milton E.,Murray, Herbert C.,Krueger, William C.,Pschigoda, Loraine M.,Duchamp, David J.
, p. 7212 - 7216 (2007/10/02)
The oxygenation of several N-cycloheptylbenzamides by fermentation with the fungus Beauveria sulfurescens (ATCC 7159) has been studied.Structures have been determined by chemical and physical methods.Enantioselectivity was observed in the oxygenation proc
REVISED STRUCTURE OF PHYSOPERUVINE, AN ALKALOID OF PHYSALIS PERUVIANA ROOTS
Ray, Anil B.,Oshima, Yoshiteru,Hikino, Hiroshi,Kabuto, Chizuko
, p. 1233 - 1236 (2007/10/02)
The previously reported physoperuvine, an alkaloid isolated from the roots of Physalis peruviana, has been found to be a hydrochloride and its structure has been settled as 3 by X-ray analysis.The forms of existence of physoperuvine, a free base, and its hydrochloride have been studied, revealing that while the salt remains exclusively in the amino-alcohol form (3), the free base is an equilibrium mixture of the amino-alcohol (1) and the amino-ketone (2), the equilibrium being shifted toward the former.
