60729-37-5

Usage

Uses

Used in Pharmaceutical Industry:
4-Bromo-5-chlorothiophene-2-carboxylic acid serves as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with potential therapeutic applications, such as antibiotics, anti-inflammatory agents, and anticancer compounds.
Used in Agrochemical Industry:
In the agrochemical sector, 4-bromo-5-chlorothiophene-2-carboxylic acid is utilized as a precursor for the production of pesticides and herbicides. Its chemical properties enable the creation of effective crop protection agents that can combat a wide range of pests and weeds.
Used in Materials Science:
4-Bromo-5-chlorothiophene-2-carboxylic acid is employed in the development of advanced materials with specific properties. Its incorporation into polymers and other materials can enhance their thermal stability, mechanical strength, and chemical resistance, making them suitable for various applications, such as in aerospace, automotive, and electronics industries.
Used in Organic Electronics and Optoelectronics:
Due to its electronic properties, 4-bromo-5-chlorothiophene-2-carboxylic acid has potential applications in the field of organic electronics and optoelectronics. It can be used in the fabrication of organic solar cells, light-emitting diodes (OLEDs), and other electronic devices, contributing to the development of more efficient and environmentally friendly technologies.

Upstream product

• 123418-67-7 1-(4-bromo-5-chlorothiophen-2-yl)ethan-1-one 
• 6310-09-4 2-acetyl-5-chlorothiophene 
• 16694-18-1 4-bromo-thiophene-2-carboxylic acid 
• 24065-33-6 5-Chlorothiophene-2-carboxylic acid 

Downstream Products

• 1047645-46-4 1,1-dimethylethyl (2-{[(4-bromo-5-chloro-2-thienyl)carbonyl]amino}-3-phenylpropyl)carbamate 
• 1047645-01-1 4-bromo-5-chloro-N-((1S)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-1-{[2-(trifluoromethyl)phenyl]methyl}ethyl)-2-thiophenecarboxamide 
• 1047645-09-9 N-((1S)-2-amino-1-{[2-(trifluoromethyl)phenyl]methyl}ethyl)-5-chloro-4-(4-bromo-1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxamide hydrochloride 
• 1047645-08-8 N-((1S)-2-amino-1-{[2-(trifluoromethyl)phenyl]methyl}ethyl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxamide hydrochloride 
• 1047645-04-4 N-((1S)-2-amino-1-{[2-(trifluoromethyl)phenyl]methyl}ethyl)-5-chloro-4-(1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxamide hydrochloride 
• 1047645-51-1 5-chloro-4-(1,4-dimethyl-1H-pyrazol-5-yl)-N-((1S)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-1-{[2-(trifluoromethyl)phenyl]methyl}ethyl)-2-thiophenecarboxamide 
• 1047645-07-7 1,1-dimethylethyl {(2S)-2-({[5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thienyl]carbonyl}amino)-3-[2-(trifluoromethyl)phenyl]propyl}carbamate 
• 1047645-10-2 1,1-dimethylethyl {(2S)-2-({[4-(4-bromo-1-methyl-1H-pyrazol-5-yl)-5-chloro-2-thienyl]carbonyl}amino)-3-[2-(trifluoromethyl)phenyl]propyl}carbamate 
• 1047645-03-3 1,1-dimethylethyl {(2S)-2-({[5-chloro-4-(1-methyl-1H-pyrazol-5-yl)-2-thienyl]carbonyl}amino)-3-[2-(trifluoromethyl)phenyl]propyl}carbamate 
• 1047643-88-8 N-((1S)-2-amino-1-{[2-(trifluoromethyl)phenyl]methyl}ethyl)-5-chloro-4-(4-bromo-1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxamide 
• 1047643-87-7 N-((1S)-2-amino-1-{[2-(trifluoromethyl)phenyl]methyl}ethyl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxamide 
• 1047644-57-4 N-((1S)-2-amino-1-{[2-(trifluoromethyl)phenyl]methyl}ethyl)-5-chloro-4-(1,4-dimethyl-1H-pyrazol-5-yl)-2-thiophenecarboxamide 
• 1047645-47-5 1,1-dimethylethyl [2-({[5-chloro-4-(1-ethyl-1H-pyrazol-5-yl)-2-thienyl]carbonyl}amino)-3-phenylpropyl]carbamate 
• 1047643-81-1 N-((1S)-2-amino-1-{[2-(trifluoromethyl)phenyl]methyl}ethyl)-5-chloro-4-(1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxamide 

Relevant academic research and scientific papers

Thiophene-2-carboxylic acid derivatives, their preparation and their use for controlling undesirable plant growth

Thiophene-2-carboxylic acid derivatives of the general formula I STR1 where R1 to R3 are each hydrogen, halogen, branched or straight-chain C1 -C6 -alkyl, C1 -C8 -alkoxy, C1 -Cs

Herbicidal Thienylureas, I

Syntheses of the title substances as potential herbicides are described by a modified Curtius degradation of corresponding thiophene carboxylic acids, obtained in turn by haloform reaction of appropriate acetyl thiophenes.Regioselective substitution reactions of thiophenes were key steps for the construction of desired substitution patterns.Structure-activity considerations show that especially the 3-thienyl ureas 36 and 38 exhibit significant herbicidal activity comparable with commercial products. - Keywords: Curtius degradation; Herbicides; Thiophenes; Ureas; Urethanes