60741-51-7

Basic information

• Product Name: 2,4-dichloro-6-methyl-3-(1-methylethyl)phenol
• Synonyms: 2,4-dichloro-6-methyl-3-(1-methylethyl)phenol;Einecs 262-400-3
• CAS NO: 60741-51-7
• Molecular Formula: C₁₀H₁₂Cl₂O
• Molecular Weight: 219.10768
• EINECS: 262-400-3
• Mol File: 60741-51-7.mol

Chemical Properties

• Boiling Point: 282.4°C at 760 mmHg
• Flash Point: 118.8°C
• Appearance: /
• Density: 1.23g/cm³
• Vapor Pressure: 0.00197mmHg at 25°C
• Refractive Index: 1.552
• CAS DataBase Reference: 2,4-dichloro-6-methyl-3-(1-methylethyl)phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-dichloro-6-methyl-3-(1-methylethyl)phenol(60741-51-7)
• EPA Substance Registry System: 2,4-dichloro-6-methyl-3-(1-methylethyl)phenol(60741-51-7)

Safety Data

• Hazardous Substances Data: 60741-51-7(Hazardous Substances Data)

Usage

Uses

Used in Personal Care Products:
Triclosan is used as an antimicrobial agent in personal care products such as soaps and toothpaste for its ability to inhibit the growth of bacteria and fungi, promoting better hygiene and reducing the risk of infections.
Used in Household Products:
In household products like cutting boards and kitchen utensils, triclosan is used as a preservative and disinfectant to prevent microbial growth and ensure cleanliness and safety in food preparation areas.
Used in Environmental Applications:
Despite its benefits, triclosan has raised concerns due to its persistence in the environment and potential to bioaccumulate in aquatic organisms. As a result, it has been banned in certain products in some countries to mitigate its impact on the environment and human health.

InChI:InChI=1/C10H12Cl2O/c1-5(2)8-7(11)4-6(3)10(13)9(8)12/h4-5,13H,1-3H3

Upstream product

• 499-75-2 carvacrol 
• 5665-94-1 4-chloro-5-isopropyl-2-methylphenol 
• 920-39-8 isopropylmagnesium bromide 
• 95717-56-9 6-acetoxy-2,4-dichloro-6-methylcyclohexa-2,4-dien-1-one 

Relevant articles and documents

Effects of Halogen Substiution on Reactions of o-Quinol Acetates with Isopropylmagnesium Bromide and Diisopropylmagnesium. Competition between Unimolecular Decomposition and Bimolecular Reactions of Radical Anions

When a single methyl substituent at C-2 or C-4 of an o-quinol acetate (1) is replaced by a halogen atom, a greatly decreased yield of the corresponding 3-isopropylphenol is obtained from reaction of 1 with isopropylmagnesium bromide.Replacement of a second methyl group by halogen results in a marked increase in the yield of the 3-isopropylphenol.Essentially identical product distributions are obtained from reactions of halogenated o-quinol acetates with concentrated and dilute Grignard solutions and with diisopropylmagnesium, in contrast to reactions with halogen-free o-quinol acetates.Reactions with hexadeuterioisopropylmagnesium bromide gave reduction products bearing increasing percentages of deuterium at C-3 as the number of bromines on the rings of the ω-quinol acetates increased.These data are consistent with reactions of halogenated o-quinol acetates, in contrast to those of halogen-free analogues, proceeding solely by SET processes.The reactions of halogen-stabilized radical anions with isopropyl radicals compete with decomposition of radical anions to phenoxy radicals.

Reactions of Halogenated o-Quinol Acetates with Isopropylmagnesium Bromide and Di-isopropylmagnesium. Mechanism for Formation of Ethers, Reduction Products, and m-Isopropylphenols

A mechanism is proposed to account for the nature and the variations in yields of products from reactions of Grignard reagents with halogenated o-quinol acetates.