60750-26-7Relevant academic research and scientific papers
Structure elaboration of isoniazid: synthesis, in silico molecular docking and antimycobacterial activity of isoniazid–pyrimidine conjugates
Kaur, Hardeep,Singh, Lovepreet,Chibale, Kelly,Singh, Kamaljit
, p. 949 - 955 (2019/11/14)
Abstract: Designing small molecule-based new drug candidates through structure modulation of the existing drugs has drawn considerable attention in view of inevitable emergence of resistance. A new series of isoniazid–pyrimidine conjugates were synthesize
Magnesium/methanol: an effective reducing agent for chemoselective reduction of pyrimidine-2(1H)-ones
Singh, Kamaljit,Singh, Kawaljit
supporting information; experimental part, p. 2219 - 2221 (2009/08/07)
Magnesium in methanol is an effective reagent for the chemoselective reduction of pyrimidine-2(1H)-ones. Other reducible functionalities such as ester and alkene of enamine ester and uriedo carbonyl remain unaffected. This constitutes the first example of
