60758-38-5

Upstream product

• 7575-35-1 N,N-bis(2-hydroxyethyl)-4-aminoaniline 
• 540-37-4 p-aminoiodobenzene 
• 107-07-3 2-chloro-ethanol 
• 120-07-0 2,2'-(phenylimino)bis[ethanol] 
• 75-21-8 oxirane 

Downstream Products

• 147622-01-3 N,N-bis(2-acetoxyethyl)-4-iodoaniline 
• 1223510-90-4 4-[N,N-bis(2-acetoxyethyl)amino]phenylacetylene 

Relevant academic research and scientific papers

Search for non-protein protease inhibitors constituted with an indole and acetylene core

A possible inhibitor of proteases, which contains an indole core and an aromatic polar acetylene, was designed and synthesized. This indole derivative has a molecular architecture kindred to biologically relevant species and was obtained through five synt

Synthesis and J-Dimer Formation of Tetrapyrazinoporphyrazines with Different Functional Groups for Potential Biomolecular Probe Applications

Though tetrapyrazinoporphyrazines (TPyzPzs) are generally presented as universal dark quenchers for oligonucleotide probes, the availability of TPyzPzs bearing different functional groups suitable for attachment to 3′, and 5′ ends or intrastrand positions remains rather limited. Therefore, a synthetic route to hexa(bis(2-methoxyethyl)amino) or hexa(diethylamino) TPyzPzs functionalized by an azide, hydroxy, or carboxy group or their combinations was developed. Studies of self-assembly into J-dimers in nonpolar solvents and their stability upon titration with pyridine (association constants, KP values, ranging 0.32–12.7×102 M?1) revealed that smaller peripheral substituents and functionalization of TPyzPzs improves the stability of J-dimers. ΦΔ and ΦF were low for the monomers (ΦFΔF=0.027, ΦΔ=0.28).

Photophysical insights on the influence of excited states reorganization processes on the visible and near infra-red luminescence of two-photon quadrupolar chromophores

We synthesized three different families of quadrupolar dyes, differing by the nature of their aromatic central cores (phenyl, fluorenyl, anthracenyl), in which we systematically varied the length of the π-conjugated backbone and the nature of the central bridge. We compared their linear and non-linear spectroscopic and photophysical features. We showed that the introduction of a diyne bridge is efficient in consistently increasing the Stokes shifts in these fluorophores, especially in high polarity solvents. By a combined theoretical and spectroscopic study we show that this feature is favoured by distortion of their π-conjugated skeleton at the electronic ground state. Unfortunately, this distortion process is generally detrimental to their fluorescence quantum yields. However, in the course of this study, we identify a particularly promising dye, that combines a large two-photon absorption (650 GM@760 nm) while keeping efficient emission (?f = 0.3) in the far-red/NIR (ca 700 nm) in polar solvent (DMSO).

Poling and crosslinking processes in NLO polymers

A series of photocrosslinkable polymers bearing hyperpolarizable side chain chromophores was synthesized, poled and evaluated on the basis of the thermal stability of Second Harmonic Generation (SHG). Photoinitiation allowed for control of the onset of curing. Crosslinking was monitored by infrared spectroscopy and optimal conversion was achieved by applying a slow temperature ramp during exposure. The ultimate stability of the poled polymers was directly related to the number of crosslinking substituents that were attached to the chromophore pendant group. With two reactive groups per chromophore significant SHG was retained at temperatures above the initial polymer glass transition temperature.

Aryl diazonium nanomagnetic sulfate and potassium iodide: An iodination process

A simple and efficient procedure for the synthesis of iodoarenes is developed which involves the sequential diazotization-iodination of aromatic amines with sodium nitrite, nanomagnetic supported sulfonic acid, and potassium iodide under solvent-free conditions at room temperature.

A Green protocol for the bromination and iodination of the aromatic compounds using H5IO6/NaBr and H5IO 6/NaI in the water

Bromination and iodination of the aromatic compounds have efficiently been carried out at room temperature and 70 °C, respectively, in short reaction times using orthoperiodic acid/sodium bromide (1:2) and orthoperiodic acid/sodium iodide (1:2) in water to prepare the corresponding halo compounds with excellent yields.

FLUORESCENT SOLVATOCHROMIC PIGMENT

The present invention presents a novel fluorescent solvatochromic dye that (1) has an ionic terminal that makes it easier to use n a hydrophilic surface or in polar solvents, (2) can be efficiently excited by commonly used Argon lasers (488 nm), (3) shift

Iodination of anilines and phenols with 18-crown-6 supported ICl 2-

A highly crystalline iodinating reagent, {[K·18-C-6]ICl 2}n, was synthesized in high yield (93%). The trihalide is supported by an 18-crown-6 macrocycle and forms a coordination polymer in the solid state. This reagent iodinates anilines and phenols efficiently under mild conditions. Controlled mono-iodination with anilines was easily achieved while poly-iodination was observed with phenols.

H5IO6/KI: A new combination reagent for iodination of aromatic amines, and trimethylsilylation of alcohols and phenols through in situ generation of iodine under mild conditions

A simple method for the in situ generation of iodine using H 5IO6/KI has been developed, and its application in silylation of OH group and iodination of aromatic amines is described.

Two-stage sensing property via a conjugated donor-acceptor-donor constitution: Application to the visual detection of mercuric ion

A conjugated donor-acceptor-donor molecule incorporating a central moiety of naphthyridine and two terminal moieties of di(hydroxyethyl)aniline connected by ethynyl bridges shows two-stage color changes on binding with mercury(II) ion in Me2SO/