60758-99-8

Basic information

• Product Name: Benzenecarbothioamide, 3-ethoxy-4-methoxy-
• CAS NO: 60758-99-8
• Molecular Formula: C10H13NO2S
• Molecular Weight: 211.285
• Mol File: 60758-99-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzenecarbothioamide, 3-ethoxy-4-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenecarbothioamide, 3-ethoxy-4-methoxy-(60758-99-8)
• EPA Substance Registry System: Benzenecarbothioamide, 3-ethoxy-4-methoxy-(60758-99-8)

Safety Data

• Hazardous Substances Data: 60758-99-8(Hazardous Substances Data)

Upstream product

• 60758-86-3 3-ethoxy-4-methoxybenzenecarbonitrile 
• 1956-36-1 3-ethoxy-4-methoxybenzaldoxime 
• 1131-52-8 3-ethoxy-4-methoxybenzaldehyde 

Downstream Products

• 115540-95-9 2-(3-ethoxy-4-methoxyphenyl)-4-(2'-pyrazinyl)thiazole 
• 115541-24-7 2-(3-methoxy-4-propoxyphenyl)-4-(1'-adamantyl)thiazole 
• 115541-17-8 2-(3-ethoxy-4-methoxyphenyl)-4-(5'-nitro-2'-furyl)thiazole 

Relevant articles and documents

Novel thiazole derivatives as inhibitors of superoxide production by human neutrophils: Synthesis and structure-activity relationships

Neutrophils have an important role in the self-defense systems of organisms through the production of superoxide. On the other hand, it has been proposed that abnormal amounts of superoxide produced by neutrophils are a serious factor in tissue injury. A series of novel thiazole derivatives was prepared and evaluated inhibitory effect on superoxide production by human neutrophils in vitro. Among these compounds, 6-[2-(3,4- diethoxyphenyl)thiazol-4-yl]-pyridine-2-carboxylic acid (OPC-6535) was selected as one of the most promising compounds. The synthesis and structure- activity relationships of these compounds are reported herein.