60760-06-7

Basic information

• Product Name: 3-CHLOROMETHYL-PHENOL
• Synonyms: 3-CHLOROMETHYL-PHENOL
• CAS NO: 60760-06-7
• Molecular Formula: C₇H₇ClO
• Molecular Weight: 142.58
• Mol File: 60760-06-7.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 259.6°C at 760 mmHg
• Flash Point: 110.8°C
• Appearance: /
• Density: 1.233g/cm³
• Vapor Pressure: 0.00794mmHg at 25°C
• Refractive Index: 1.569
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• PKA: 9.61±0.10(Predicted)
• CAS DataBase Reference: 3-CHLOROMETHYL-PHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CHLOROMETHYL-PHENOL(60760-06-7)
• EPA Substance Registry System: 3-CHLOROMETHYL-PHENOL(60760-06-7)

Safety Data

• Hazardous Substances Data: 60760-06-7(Hazardous Substances Data)

Usage

General Description

3-Chloromethyl-phenol, also known as 3-Chlorophenyl methyl ether, is a chemical compound with the molecular formula C7H7ClO. Its molecular weight is 144.583 g/mol. This synthetic chemical is mainly used in the production of pharmaceuticals, dyes, and other organic materials. It is also used as a solvent. Exposure to this compound can be harmful and may cause skin, eye, and respiratory irritation. Therefore, handling and disposal of this compound should be done in accordance with safety guidelines and regulations.

InChI:InChI=1/C7H7ClO/c8-5-6-2-1-3-7(9)4-6/h1-4,9H,5H2

Upstream product

• 620-24-6 3-Hydroxybenzyl alcohol 
• 100-83-4 meta-hydroxybenzaldehyde 

Downstream Products

• 126328-84-5 tert-butyl (3-(chloromethyl)phenoxy)dimethylsilane 
• 478374-32-2 {4'-[3-(3-Chlorophenoxy)-1-propynyl]biphenyl-3-yl}acetic acid 
• 187994-07-6 ethyl 1-(3-methoxybenzyl)-2-piperidinecarboxylate 
• 187994-14-5 2-[5-imino-1-(3-methoxybenzyl)-2-pyrrolidinyl]-4,5-diphenyloxazole 
• 187994-27-0 1-(3-methoxybenzyl)-5-(4,5-diphenyloxazol-2-yl)pyrrolidin-2-one 
• 138076-96-7 3'-Hydroxystilbene-2-carboxylic acid 
• 37568-80-2 (+/-)-3,4-Dihydro-3-(3'-hydroxyphenyl)isocoumarin 
• 867187-59-5 ethyl 1-oxo-3-phenyl-6-(3-phenylpropoxy)-1H-indene-2-carboxylate 
• 949593-63-9 1-oxo-6-phenethyloxy-3-phenyl-1H-indene-2-carboxylic acid ethyl ester 

Relevant articles and documents

Examination of a Series of Ir and Rh PXL Pincer Complexes as (Pre)catalysts for Aromatic C-H Borylation

This work follows a previously published study of high-turnover aromatic C-H borylation by Ir complexes supported by POCOP-type ligands incorporating-PiPr2 side donors (L1-L3) using HBpin in the presence of olefins. A variety of pincer-supported Ir and Rh

Pyrrolopyrazole derivative, preparation method and medical application thereof

The invention relates to pyrrolopyrazole derivative, a preparation method and application thereof in medicines. Specifically, the invention relates to a new pyrrolopyrazole derivative as shown in a general formula (I), a preparation method and application of the pyrrolopyrazole derivative or a pharmaceutical composition containing the pyrrolopyrazole derivative as a therapeutic agent, particularlyas a gastric acid secretion inhibitor and potassium-competitive acid blockers (P-CABs) in biological medicines. Specifically, the substituents (R1, R2, R3 and R4) in the general formula (I) are the same as the definitions in the specification.

Continuous Flow Preparation of (Hetero)benzylic Lithiums via Iodine-Lithium Exchange Reaction under Barbier Conditions

Herein we report the generation of benzylic lithiums via an iodine-lithium exchange reaction on benzylic iodides performed in continuous flow using tBuLi as the exchange reagent. The resulting benzylic lithium species are trapped in situ by carbonyl electrophiles under Barbier conditions, resulting in benzylic secondary and tertiary alcohols. This flow procedure further allows the generation of highly reactive heterobenzylic lithium compounds, which are difficult to generate under batch conditions. A general scale-up was possible without further optimization.