867187-58-4Relevant articles and documents
Combining spontaneous polymerization and click reactions for the synthesis of polymer brushes: A grafting onto approach
Cappelli, Andrea,Grisci, Giorgio,Paolino, Marco,Castriconi, Federica,Giuliani, Germano,Donati, Alessandro,Lamponi, Stefania,Mendichi, Raniero,Boccia, Antonella Caterina,Samperi, Filippo,Battiato, Salvatore,Paccagnini, Eugenio,Gentile, Mariangela,Licciardi, Mariano,Giammona, Gaetano,Vomero, Salvatore
supporting information, p. 9710 - 9721 (2013/07/26)
Two novel benzofulvene monomers bearing propargyl or allyl groups have been synthesized by means of readily accessible reactions, and were found to polymerize spontaneously by solvent removal, in the apparent absence of catalysts or initiators, to give the corresponding polybenzofulvene derivatives bearing clickable propargyl or allyl moieties. The clickable propargyl and allyl groups were exploited in appropriate click reactions to develop a powerful and versatile grafting onto synthetic methodology for obtaining tailored polymer brushes. A clean sweep: Two novel benzofulvene monomers bearing either propargyl or allyl groups were found to polymerize spontaneously by solvent removal in the absence of catalysts or initiators to give the corresponding polybenzofulvene derivatives bearing clickable propargyl or allyl moieties. These derivatives were modified using click reactions, thus demonstrating a grafting onto methodology for the synthesis of tailored polymer brushes (see figure). Copyright
Indenone derivatives: A novel template for peroxisome proliferator- activated receptor γ (PPARγ) agonists
Ahn, Jin Hee,Shin, Mi Sik,Jung, Sun Ho,Kang, Seung Kyu,Kim, Kwang Rok,Rhee, Sang Dal,Jung, Won Hoon,Yang, Sung Don,Kim, Seung Jun,Woo, Joo Rang,Lee, Jeong Hyung,Cheon, Hyae Gyeong,Kim, Sung Soo
, p. 4781 - 4784 (2007/10/03)
Agonists of peroxisome proliferator-activated receptor γ(PPAR γ) are of interest as a treatment for diabetes, which prompted the identification of a new class of non-TZD PPAR γ agonist. Moreover, compound 14c has displayed the most active agonistic activi
INDENE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF
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Page/Page column 38, (2010/02/14)
The inventive indene derivatives of formula (I) are capable of selectively modulating the activities of peroxisome proliferator activated receptors (PPARs), causing no adverse side effects, and thus, they are useful for the treatment and prevention of disorders modulated by PPARs, i.e., metabolic syndromes such as diabetes, obesity, arteriosclerosis, hyperlipidemia, hyperinsulinism and hypertension, inflammatory diseases such as osteoporosis, liver cirrhosis and asthma, and cancer.