60761-30-0

Upstream product

• 60771-27-9 p-Nitrobenzyl 7-(phenoxyacetamido)-3-methylenecepham-4-carboxylate 1β-oxide 
• 61375-82-4 (6R)-3-methylene-5ξ,8-dioxo-7t-(2-phenoxy-acetylamino)-(6rH)-5λ⁴-thia-1-aza-bicyclo[4.2.0]octane-2c-carboxylic acid 4-nitro-benzyl ester 
• 60771-27-9 (4R,6R,7R)-4-nitrobenzyl 3-methylene-7-phenoxyacetamidocepham-4-carboxylate-1-oxide 

Downstream Products

• 39876-55-6 (6R)-3-bromomethyl-8-oxo-7t-(2-phenoxy-acetylamino)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 62987-29-5 (6R)-3-iodomethyl-8-oxo-7t-(2-phenoxy-acetylamino)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 129544-60-1 C₁₈H₂₀N₄O₅S 
• 129544-61-2 C₂₄H₂₃N₅O₇S 
• 130994-93-3 (2R,7R,8R)-3-Methylene-9-oxo-8-(2-phenoxy-acetylamino)-6-thia-1-aza-bicyclo[5.2.0]nonane-2,5,5-tricarboxylic acid dimethyl ester 4-nitro-benzyl ester 
• 130994-95-5 (2R,5R,7R,8R)-3-Methylene-9-oxo-8-(2-phenoxy-acetylamino)-6-thia-1-aza-bicyclo[5.2.0]nonane-2,5-dicarboxylic acid 5-tert-butyl ester 2-(4-nitro-benzyl) ester 
• 78963-68-5 (2R,6R,7R)-7-Amino-3-methylene-8-oxo-5-thia-1-aza-bicyclo[4.2.0]octane-2-carboxylic acid 4-nitro-benzyl ester; hydrochloride 
• 114138-89-5 (2R,6R,7R)-1-aza-3-methylene-7-<5R-5-p-nitrobenzyloxycarbonylamino-5-p-nitrobenzyloxycarbonylpentaamido>-8-oxo-5-thia-bicyclo<4.2.0>octane-2-carboxylic acid p-nitrobenzyl ester 
• 62987-31-9 (6R)-3-(1-methyl-1H-tetrazol-5-ylsulfanylmethyl)-8-oxo-7t-(2-phenoxy-acetylamino)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 62987-30-8 (6R)-3-acetoxymethyl-8-oxo-7t-(2-phenoxy-acetylamino)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 130994-98-8 (5R,7R,8R)-3-Methyl-9-oxo-8-(2-phenoxy-acetylamino)-6-thia-1-aza-bicyclo[5.2.0]non-2-ene-2,5-dicarboxylic acid 5-ethyl ester 2-(4-nitro-benzyl) ester 
• 130994-97-7 (7R,8R)-3-Methyl-9-oxo-8-(2-phenoxy-acetylamino)-6-thia-1-aza-bicyclo[5.2.0]non-2-ene-2,5,5-tricarboxylic acid dimethyl ester 
• 130994-99-9 (5R,7R,8R)-8-Amino-3-methyl-9-oxo-6-thia-1-aza-bicyclo[5.2.0]non-2-ene-2,5-dicarboxylic acid 5-ethyl ester 2-(4-nitro-benzyl) ester 
• 130995-00-5 (5R,7R,8R)-8-((R)-2-Amino-2-phenyl-acetylamino)-3-methyl-9-oxo-6-thia-1-aza-bicyclo[5.2.0]non-2-ene-2,5-dicarboxylic acid 5-ethyl ester 

Relevant academic research and scientific papers

Method of preparation of 3-methylene cepham compounds

A method for the preparation of 3-methylene cepham compounds which comprises reacting 3-halomethyl butenoate derivatives of thiazolinoazetidinone with an aqueous acid solution in a mixed organic solvent.