60767-69-3

Basic information

• Product Name: 4-Chloro-3-formylbenzenesulfonic acid
• Synonyms: 4-Chloro-3-formylbenzenesulfonic acid;Sodium 2-formylbenzene-1,4-disulfonate
• CAS NO: 60767-69-3
• Molecular Formula: C₇H₅ClO₄S
• Molecular Weight: 220.6302
• Mol File: 60767-69-3.mol

Chemical Properties

• Appearance: /
• Density: 1.624±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -1.11±0.50(Predicted)
• CAS DataBase Reference: 4-Chloro-3-formylbenzenesulfonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chloro-3-formylbenzenesulfonic acid(60767-69-3)
• EPA Substance Registry System: 4-Chloro-3-formylbenzenesulfonic acid(60767-69-3)

Safety Data

• Hazardous Substances Data: 60767-69-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4-Chloro-3-formylbenzenesulfonic acid is used as a building block for the synthesis of various pharmaceuticals. Its unique structure allows it to be a versatile intermediate in the development of new drugs.
Used in Dye Industry:
4-Chloro-3-formylbenzenesulfonic acid is used as a precursor in the production of dyes. Its chemical properties enable it to be a key component in creating a wide range of colors.
Used in Organic Intermediates:
4-Chloro-3-formylbenzenesulfonic acid is used as an organic intermediate in the synthesis of various organic compounds. Its reactivity and functional groups make it a valuable component in organic chemistry.
Used as a Reagent in Chemical Reactions:
4-Chloro-3-formylbenzenesulfonic acid is used as a reagent in chemical reactions, particularly in the formation of aromatic compounds. Its ability to participate in various chemical processes makes it a useful tool in the laboratory.
Safety Precautions:
4-Chloro-3-formylbenzenesulfonic acid is considered to be a hazardous substance, and proper safety measures should be taken when handling it. This includes wearing appropriate personal protective equipment and following safety guidelines to minimize risks.

Upstream product

• 89-98-5 2-chloro-benzaldehyde 
• 104-88-1 4-chlorobenzaldehyde 

Downstream Products

• 911358-03-7 2-(bis(4-(diethylamino)phenyl)methyl)benzene-1,4-disulfonic acid 

Relevant articles and documents

ISOSULFAN BLUE, ITS CRYSTALLINE FORM AND PROCESS FOR PREPARATION THEREOF

The invention relates to an improved process for the preparation N-[4-[[4-(diethyl amino) phenyl] (2,5-disulfophenyl)methylene]-2,5-cyclohexadien-1-ylidene]-N- ethylethanaminium inner salt sodium salt (Isosulfan blue) of formula I. The invention also relates to highly pure novel crystalline form of Isosulfan blue (I) hydrate and its process for the preparation thereof. The invention also relates to an improved process for the preparation of Isosulfan blue sodium hydrate having not more than 0.2% of desethyl impurity of formula A.

Palladium-Catalyzed 2,2,2-Trifluoroethoxylation of Aromatic and Heteroaromatic Chlorides Utilizing Borate Salt and the Synthesis of a Trifluoro Analogue of Sildenafil

A simple and convenient method was developed for the introduction of a 2,2,2-trifluoroethoxy group to various aromatic and heteroaromatic systems. The novel process utilizes aromatic chlorides as substrates, and tetrakis(2,2,2-trifluoroethoxy) borate salt as an inexpensive and readily available fluoroalkoxy source in a palladium-catalyzed cross-coupling reaction. The power of the developed methodology was demonstrated in the synthesis of a fluorous derivative of Sildenafil.

AN IMPROVED PROCESS FOR THE PREPARATION OF ISOSULFAN BLUE

The present invention relates to process for preparation of Isosulfan blue (Formula I) substantially free from desethyl impurity. (I)

A PROCESS FOR THE PREPARATION OF ISOSULPHAN BLUE

A process for the preparation of Isosulphan Blue is disclosed. The process comprises the following steps: Sulphonating orthochlorobenzaldehyde, treatment with sodium sulphite, basification, condensation and oxidation to obtain Isosulphan Blue.