60769-26-8

Upstream product

• 57296-59-0 2,3-dichloro-4-(2-phenylacryloyl)-anisole 
• 59043-83-3 2,3-dichloro-4-phenylacetylanisole 

Downstream Products

• 88494-66-0 (S)-(+)-6,7-dichloro-5-methoxy-2-methyl-2-phenyl-1-indanone 
• 95189-64-3 (R)-6,7-Dichloro-5-methoxy-2-methyl-2-phenyl-indan-1-one 
• 66015-42-7 2-cyclopentyl-2-phenyl-5-methoxy-6,7-dichloro-1-indanone 
• 66015-41-6 2-ethyl-2-phenyl-5-methoxy-6,7-dichloro-1-indanone 
• 57296-78-3 2,2-diphenyl-5-methoxy-6,7-dichloro-1-indanone 
• 67976-22-1 2-phenyl-5-hydroxy-6,7-dichloro-1-indanone 
• 66015-48-3 2-ethyl-2-phenyl-5-hydroxy-6,7-dichloro-1-indanone 
• 57296-79-4 2,2-diphenyl-5-hydroxy-6,7-dichloro-1-indanone 
• 66015-49-4 2-cyclopentyl-2-phenyl-5-hydroxy-6,7-dichloro-1-indanone 
• 67995-02-2 (1-oxo-2-phenyl-6,7-dichloro-5-indanyloxy)acetic acid 
• 66036-05-3 (1-oxo-2-ethyl-2-phenyl-6,7-dichloro-5-indanyloxy)acetic acid 
• 57296-80-7 (1-oxo-2,2-diphenyl-6,7-dichloro-5-indanyloxy)acetic acid 
• 66015-24-5 (1-oxo-2-cyclopentyl-2-phenyl-6,7-dichloro-5-indanyloxy)acetic acid 
• 56049-88-8 (+/-)-Indacrinone 

Relevant academic research and scientific papers

Preparation of acrylophenones and 2-alkyl indanones utilizing hexamethylenetetramine as an inexpensive Mannich reagent

Hexamethylenetetramine/acetic anhydride-promoted α-methylenation of aryl alkyl ketones followed by acid-catalyzed cyclization of the resulting acrylophenones produce 2-alkyl indanones in excellent yields.

(1-Oxo-2-aryl or thienyl-2-substituted-5-indanyloxy (or thio) alkanoic acids, and derivatives thereof

[1-Oxo-2-aryl or thienyl-2-substituted-5-indanyloxy (or thio)]aklanoic acid, derivatives thereof, their salts, esters and amides are disclosed. The products display a dual pharmaceutical utility in that they exhibit diuretic, saluretic and uricosuric activity. Also disclosed are processes for the preparation of such [1-oxo-2-aryl or thienyl-2-substituted-5-indanyloxy (or thio)]alkanoic acids, pharmaceutical compositions comprising therapeutically effective amounts of such compounds and methods of treatment comprising administering such compounds and compositions.

6-Oxo-7-substituted and 7,7-disubstituted-6H-indeno-[5,4-b]furan (and thiophene) carboxylic acids

6-Oxo-7,7-disubstituted-1,2,7,8-tetrahydro (and 7,8-dihydro)-6H-indeno-[5,4-b]furan (and thiophene)carboxylic acids, the salt, ester and amide derivatives thereof and combinations of these compounds with antikaluretic agents are disclosed having diuretic-saluretic, uricosuric and antihypertensive activity.