67995-02-2

Upstream product

• 64-69-7 Iodoacetic acid 
• 67976-22-1 2-phenyl-5-hydroxy-6,7-dichloro-1-indanone 
• 59043-83-3 2,3-dichloro-4-phenylacetylanisole 
• 57296-59-0 2,3-dichloro-4-(2-phenylacryloyl)-anisole 
• 60769-26-8 2-Phenyl-5-methoxy-6,7-dichloro-1-indanone 

Downstream Products

• 56049-88-8 (+/-)-Indacrinone 
• 66015-31-4 [1-Oxo-2-(4-aminomethylphenyl)-2-methyl-6,7-dichloro-5-indanyloxy]acetic acid 
• 66015-32-5 [1-oxo-2-methyl-2-(4-sulfamoylphenyl)-6,7-dichloro-5-indanyloxy]acetic acid 
• 66015-59-6 [1-Oxo-2-(4-chlorosulfonylphenyl)-2-methyl-6,7-dichloro-5-indanyloxy]acetic acid 

Relevant academic research and scientific papers

(1-Oxo-2-aryl or thienyl-2-substituted-5-indanyloxy (or thio) alkanoic acids, and derivatives thereof

[1-Oxo-2-aryl or thienyl-2-substituted-5-indanyloxy (or thio)]aklanoic acid, derivatives thereof, their salts, esters and amides are disclosed. The products display a dual pharmaceutical utility in that they exhibit diuretic, saluretic and uricosuric activity. Also disclosed are processes for the preparation of such [1-oxo-2-aryl or thienyl-2-substituted-5-indanyloxy (or thio)]alkanoic acids, pharmaceutical compositions comprising therapeutically effective amounts of such compounds and methods of treatment comprising administering such compounds and compositions.