60812-46-6

Usage

Chemical Class

Alkylamines

Type of Amine

Tertiary amine

Substitution on Benzene Ring

3-Methoxy group

Alkyl Group

2-Methylpropan-1-amine

Usage

Organic synthesis and pharmaceutical research

Potential Applications

Drug development

Known for

Therapeutic effects, promising candidate for medicinal chemistry.

Upstream product

• 17653-93-9 2-(3'-Methoxyphenyl)-2-methylpropionitrile 

Downstream Products

• 62245-15-2 6-methoxy-4,4-dimethyl-1,2,3,4-tetrahydro-isoquinoline 

Relevant academic research and scientific papers

COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY

The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of GPR119.

ACYCLIC IKUR INHIBITORS

A compound of formula I wherein R1, R2, R3, R4 and R5 are described herein.

Isoquinoline derivatives

Compounds of formula (I) wherein: R1represents a substituent selected from: a hydrogen or halogen atom; a hydroxy, cyano, nitro, trifluoromethyl, trifluoromethoxy, trifluoromethanesulfonyloxy, pentafluoroethyl, C1-4alkyl, C1-4alkoxy, arylC1-4alkoxy, C1-4alkylthio, C1-4alkoxyC1-4alkyl, C3-6cycloalkylC1-4alkoxy, C1-4alkanoyl, C1-4alkoxycarbonyl, C1-4alkylsulfonyl, C1-4alkylsulfonyloxy, C1-4alkylsulfonylC1-4alkyl, arylsulfonyl, arylsulfonyloxy, arylsulfonylC1-4alkyl, C1-4alkylsulfonamido, C1-4alkylamido, C1-4alkylsulfonamidoC1-4alkyl, C1-4alkylamidoC1-4alkyl, arylsulfonamido, arylcarboxamido, arylsulfonamidoC1-4alkyl, arylcarboxamidoC1-4alkyl, aroyl, aroylC1-4alkyl, or arylC1-4alkanoyl group; a group R5OCO(CH2)p, R5(CON(R6)(CH2)p, R5R6NCO(CH2)p or R5R6NSO2(CH2)p where each of R5and R6independently represents a hydrogen atom or a C1-4alkyl group or R5R6forms part of a C3-6azacycloalkane or C3-6(2-oxo)azacycloalkane ring and p represents zero or an integer from 1 to 4; or a group Ar3—Z, wherein Ar3represents an optionally substituted phenyl ring or an optionally substituted 5- or 6-membered aromatic heterocyclic ring and Z representsa bond, O, S, or Ch2; R2 represents a hydrogen atom or a C1-4alkyl group; R3 and R4 each independently represent a C1-4alkyl group, q is 1 or 2; A represents a group of the formula (a), (b), (c), or (d).