17653-93-9

Basic information

• Product Name: 2-(3-METHOXYPHENYL)-2-METHYLPROPANENITRILE
• Synonyms: 2-(3-METHOXYPHENYL)-2-METHYLPROPANENITRILE
• CAS NO: 17653-93-9
• Molecular Formula: C₁₁H₁₃NO
• Molecular Weight: 175.23
• Product Categories: Phenyls & Phenyl-Het;Phenyls & Phenyl-Het
• Mol File: 17653-93-9.mol
• Article Data: 21

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(3-METHOXYPHENYL)-2-METHYLPROPANENITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-METHOXYPHENYL)-2-METHYLPROPANENITRILE(17653-93-9)
• EPA Substance Registry System: 2-(3-METHOXYPHENYL)-2-METHYLPROPANENITRILE(17653-93-9)

Safety Data

• Hazardous Substances Data: 17653-93-9(Hazardous Substances Data)

Usage

Nitrile compound

Contains a cyano group (-C≡N)
A nitrile group is a functional group consisting of a carbon atom triple-bonded to a nitrogen atom, giving the compound unique chemical properties.

Intermediate in synthesis

Used in the production of pharmaceuticals and agrochemicals
As an intermediate, 2-(3-Methoxyphenyl)-2-methylpropanenitrile serves as a building block for creating more complex molecules in the synthesis of drugs and pesticides.

Building block for organic compounds

Can be used to create new compounds with specific properties and applications
The chemical structure of the compound allows it to react with other molecules, forming new organic compounds with tailored characteristics for various uses.

Potential applications in other industries

Beyond pharmaceuticals and agrochemicals
The compound may have uses in industries such as materials science, due to its unique structure and reactivity.

Proper handling and safety measures

Importance of safety when working with the compound
As with any chemical, it is crucial to follow proper handling procedures and safety precautions to minimize risks associated with the use of 2-(3-Methoxyphenyl)-2-methylpropanenitrile.

Upstream product

• 19924-43-7 3-methoxyphenylacetonitrile 
• 74-88-4 methyl iodide 
• 78-82-0 Isobutyronitrile 
• 456-49-5 1-fluoro-3-methoxybenzene 
• 586-37-8 1-(3-Methoxyphenyl)ethanone 
• 25108-57-0 3-(1-methylethenyl)anisole 
• 75-86-5 2-hydroxy-2-methylpropanenitrile 
• 12116-44-8 (η6-anisol)tricarbonyl chromium 
• 50654-53-0 2-lithio-2-methylpropionitrile 
• 22739-77-1 2-Methylpropionitrile-d7 

Downstream Products

• 60812-46-6 2-(3-methoxyphenyl)-2-methylpropane-1-amine 
• 1067192-48-6 2-(3-methoxy-4-nitrophenyl)-2-methylpropanenitrile 
• 1200397-23-4 2-(3-(2,6-dimethylbenzyloxy)phenyl)-2-methylpropanoic acid 
• 1200397-41-6 2-(3-(2,6-dimethylbenzyloxy)phenyl)-2-methylpropanenitrile 
• 1200397-42-7 2-(3-(2,6-dimethylbenzyloxy)phenyl)-2-methylpropanal 
• 1620518-38-8 2-(3-hydroxyphenyl)-1-[5-(3-hydroxyphenyl)thiophen-2-yl]-2-methylpropan-1-one 
• 1620518-37-7 2-(3-methoxyphenyl)-1-[5-(3-methoxyphenyl)thiophen-2-yl]-2-methylpropan-1-one 
• 184906-32-9 3,3-Dimethyl-5-(1-phenyl-1H-tetrazol-5-yloxy)-2,3dihydroisoindol-1-one 
• 184906-29-4 5-methoxy-3,3-dimethylisoindolin-1-one 
• 109138-26-3 1-(1-Isocyanato-1-methylethyl)-3-methoxybenzene 
• 184906-31-8 5-Hydroxy-3,3-dimethyl-2,3-dihydroisoindol-1-one 
• 19194-52-6 3,3-dimethylisoindolin-1-one 
• 17653-95-1 2-(3-methoxyphenyl)-2-methyl-propan-1-ol 
• 17653-94-0 α-methyl-α-(3-methoxyphenyl)proprionic acid 

Relevant articles and documents

Thermodynamic Control of Regioselectivity in the Addition of Carbanions to (Arene)tricarbonylchromium Complexes

The results of a study of question of kinetic or thermodynamic control of the addition of carbon nucleophiles to (arene)Cr(CO)3 complexes are presented. 2-Lithio-2-methylpropionitrile (1) is shown to add reversibly to (naphthalene)Cr(CO)3 (2), (5,8-dimeth

Synthesis of Tertiary Benzylic Nitriles via Nickel-Catalyzed Markovnikov Hydrocyanation of α-Substituted Styrenes

The Markovnikov hydrocyanation of α-substituted styrenes enables the synthesis of tertiary benzylic nitriles under nickel catalysis. The Lewis-acid-free transformation features an unprecedented functional groups tolerance, including the-OH and-NH2 groups. A broad range of tertiary benzylic nitriles were obtained in good to excellent yields. In addition, an asymmetric version of this reaction was preliminarily investigated.

Diphenyl-aminopyrimidine compound for inhibiting kinase activity

The invention relates to a diphenyl-aminopyrimidine compound with an inhibiting function on protein tyrosine kinase, a pharmaceutical composition containing the diphenyl-aminopyrimidine compound, andpreparation and application of the diphenyl-aminopyrimidine compound, in particular to a compound shown as the formula (I) and pharmaceutically acceptable salt or crystal forms or prodrugs or metabolin or aquo-complex or solvate or isotope derivatives thereof, wherein R1, R2, R5, R6, R7, R8 and W are defined as the description. The compound can be used for treating ALK-mediated cancer related symptoms, such as non-small cell lung cancer or breast cancer or neural tumors or esophagus cancer or soft tissue cancer or lymphoma or leukemia. The formula is shown in the specification.