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• 71099-84-8 α-Methylzimtsaeureanilid 
• 80818-45-7 N-phenyl methyl-2 phenyl-3 propene-2 amide 
• 73859-94-6 trans-2,3-dihydro-3-methyl-2-phenyl-1,5-benzothiazepin-4(5H)-one 
• 72293-20-0 Toluene-4-sulfonic acid (2R,3R)-4-oxo-2-phenyl-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-ylmethyl ester 
• 137-07-5 2-amino-benzenethiol 
• 35086-87-4 (E)-2-methyl-3-phenylacryloyl chloride 
• 300-57-2 allylbenzene 
• 201230-82-2 carbon monoxide 
• 62-53-3 aniline 
• 1009-67-2 2-methyl-3-phenylpropanoic acid 
• 72293-17-5 trans-2,3-dihydro-3-(4-methylpiperazinylmethyl)-2-phenyl-1,5-benzothiazepin-4(5H)-one 
• 72293-35-7 Methanesulfonic acid (2R,3R)-4-oxo-2-phenyl-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-ylmethyl ester 
• 72293-16-4 trans-3-chloromethyl-2,3-dihydro-2-phenyl-1,5-benzothiazepin-4(5H)-one 
• 72293-09-5 trans-2,3-dihydro-3-hydroxymethyl-2-phenyl-1,5-benzothiazepin-4(5H)-one 

Relevant academic research and scientific papers

Organic ligand-free carbonylation reactions with unsupported bulk Pd as catalyst

Herein, surprising results for bulk Pd-catalyzed carbonylation reactions are presented. Three types of carbonylation reactions can be realized efficiently under organic ligand-free conditions, namely, hydroaminocarbonylation of olefins, aminocarbonylation of aryl iodides and oxidative carbonylation of amines, which almost cover all the known mechanisms in carbonylation reactions. Notably, the bulk Pd catalyst system exhibited better catalytic activity than the classical homogeneous PdCl2/(2-OMePh)3P catalyst system. This study will create a momentous and new field of green carbonylation reactions.

METHOD FOR PRODUCING CARBOXYLIC ACID AMIDE

PROBLEM TO BE SOLVED: To use arylboronic acid with a chemical structure more simpler than that of the conventional one in a method for producing carboxylic acid amide. SOLUTION: Provided is a method for producing carboxylic acid amide capable of obtaining carboxylic acid amide by dehydration condensation reaction between carboxylic acid and amine. As the carboxylic acid, carboxylic acid having two or more hydrogen atoms at the α position, carboxylic acid having hydrogen atoms and a methyl group at the α position, α, β-unsaturated carboxylic acid or aromatic carboxylic acid is used. Further, B(OH)3, PhB(OH)2 or the like are used as a catalyst, and 4-dimethylaminopyridine, its N-oxide or the like are used as an additive. SELECTED DRAWING: None COPYRIGHT: (C)2016,JPOandINPIT

Acid-free regioselective aminocarbonylation of alkenes

An efficient method for the synthesis of N-aryl monosubstituted carboxamides via the Pd-catalyzed carbonylation of alkenes with CO and amines is described. Mechanistic insights for this highly selective reaction are provided. This journal is the Partner O

Selective Reduction of αβ-Olefinic Amides and Lactams by Magnesium and Methanol

αβ-Olefinic amides with various substitution patterns at the carbon-carbon double bond and at nitrogen are all reduced to the corresponding saturated amides by magnesium and methanol.The same reducing system reduces N-benzyl-8-azabicyclonona-1(6),3-dien-7-ones at the conjugated double bond to give mixtures of the cis- and trans-dihydro-derivatives; the isolated, non-conjugated double bond is not reduced, even in the 3,4-diphenylsubstituted compound.Magnesium and methanol reduces quinolin-2(1H)-ones to their 3,4-dihydro-derivatives, and 5,6,7,8-tetrahydroquinolin-2(1H)-one to a mixture of two dihydro-derivatives.

CONJUGATE ADDITION OF ORGANOLITHIUM REAGENTS TO ACRYLANILIDE ANIONS

Phenyllithium, n-butyllithium, and t-butyllithium were found to add to substituted acrylanilide anions to give the 1,4-addition products in fair to good yields.

The selective reduction of αβ-olefinic amides

The carbon-carbon double bond in αβ-olefinic amides can be selectively reduced by magnesium and methanol; other olefinic bonds, including those of the stilbene type are unaffected.