6087-43-0

Basic information

• Product Name: methyl 3,4,6-tri-O-acetyl-2-deoxy-β-D-lyxo-hexopyranoside
• CAS NO: 6087-43-0
• Molecular Weight: 304.297
• Mol File: 6087-43-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: methyl 3,4,6-tri-O-acetyl-2-deoxy-β-D-lyxo-hexopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3,4,6-tri-O-acetyl-2-deoxy-β-D-lyxo-hexopyranoside(6087-43-0)
• EPA Substance Registry System: methyl 3,4,6-tri-O-acetyl-2-deoxy-β-D-lyxo-hexopyranoside(6087-43-0)

Safety Data

• Hazardous Substances Data: 6087-43-0(Hazardous Substances Data)

Upstream product

• 4163-60-4 β-D-galactose peracetate 
• 108-24-7 acetic anhydride 
• 67-56-1 methanol 
• 4098-06-0 triacetyl-D-galactal 

Relevant articles and documents

TMSBr-mediated solvent- and work-up-free synthesis of α-2-deoxyglycosides from glycals

The thio-additions of glycals were efficiently promoted by a stoichiometric amount of trimethylsilyl bromide (TMSBr) to produce S-2-deoxyglycosides under solvent-free conditions in good to excellent yields. In addition, with triphenylphosphine oxide as an additive, the TMSBr-mediated direct glycosylations of glycals with a large range of alcohols were highly α-selective.

The use of tri-O-acetyl-D-glucal and -D-galactal in the synthesis of 3-acetamido-2,3-dideoxyhexopyranoses and -hexopyranosides.

Addition of hydrazoic acid to alpha,beta-unsaturated aldehydes derived from tri-O-acetyl-D-glucal and -D-galactal gave 3-azido-2,3-dideoxyhexopyranoses. These were converted into 1,4,6-tri-O-acetyl-3-azido-2,3-dideoxyhexopyranoses as well as methyl and ethyl glycosides. Hydrogenation of the proamine group in 3-azido-2,3-dideoxy derivatives provided different 3-amino and 3-acetamido sugars. The configuration and conformation of all products were established on the basis of the 1H and 13 C NMR, IR and polarimetric data.