6089-08-3

Upstream product

• 536-74-3 phenylacetylene 
• 111119-62-1 Diethyl-methyl-(3-phenyl-prop-2-ynyl)-ammonium; iodide 
• 1794-48-5 1-bromo-3-phenylprop-2-yne 
• 70-55-3 toluene-4-sulfonamide 
• 108-18-9 diisopropylamine 
• 21541-60-6 3-phenylprop-2-ynyl 4-methylbenzenesulfonate 
• 1007-47-2 (phenylethynyl)dimethylaluminum 
• 106-54-7 p-Chlorothiophenol 
• 124-38-9 carbon dioxide 
• 3355-31-5 1-chloro-3-phenyl-2-propyne 

Relevant academic research and scientific papers

Method for preparing diynes and analogs thereof

The invention discloses a method for preparing multiple diyne and derivatives thereof. Propargyl bromide compounds IV and terminal alkyne compounds V are used as substrates and react in N,N-dimethylacetamide at 40 DEG C in a nitrogen environment under the

Designing Synergistic Nanocatalysts for Multiple Substrate Activation: Interlattice Ag-Fe3O4 Hybrid Materials for CO2-Inserted Lactones

Multimetallic architectures that combine chemically diverse materials to affect tandem reactions within a single scaffold drive future nanocatalyst development. Here, we show the unique, interlattice growth of the small molecule activating Ag guest within

Highly dispersed Ni2P nanoparticles on N,P-codoped carbon for efficient cross-dehydrogenative coupling to access alkynyl thioethers

An ultrafine Ni2P (a metal-rich interstitial phosphide compound) nanoparticles with a narrow size distribution homogeneously dispersed on N,P-codoped carbon was developed for efficient synthesis of alkynyl thioethers via base- and ligand-free cross-dehydrogenative coupling (CDC) of terminal alkynes and thiols using atmospheric air as the oxidant under mild conditions. A remarkable catalytic performance with good functional group compatibility, broad substrate scope and high stability is accomplished. Pyridinic N atoms are identified as basic sites for facilitating the activation of terminal alkynes via hydrogen bonding interactions and play a key role in the success of this base- and ligand-free CDC reaction.

Gold-Catalyzed Cascade Reaction of Skipped Diynes for the Construction of a Cyclohepta[b]pyrrole Scaffold

A gold-catalyzed cascade reaction of skipped diynes (1,4-diynes) and pyrroles has been developed. This reaction proceeds by the consecutive regioselective hydroarylation of two alkynes with a pyrrole, followed by a 7-endo-dig cyclization to give 1,6-dihydrocyclohepta[b]pyrroles in good yields. The direct synthesis of cyclohepta[b]indoles using indole nucleophiles has also been reported.

Cu-catalyzed aerobic oxidative three-component coupling route to N -sulfonyl amidines via an ynamine intermediate

Cu-catalyzed aerobic oxidative three-component coupling of a terminal alkyne, secondary amine, and sulfonamide enables efficient synthesis of amidines. The use of Cu(OTf)2 (5 mol %) produces amidines selectively without Glaser-Hay alkyne homocoupling products. Preliminary studies suggest that the reaction pathway involves initial oxidative coupling of the terminal alkyne with the secondary amine, followed by hydroamidation of the ynamine intermediate with the sulfonamide.