60891-25-0

Basic information

• Product Name: 3-Cyclohexene-1-carboxylic acid, 3-methoxy-5-oxo-, methyl ester
• CAS NO: 60891-25-0
• Molecular Formula: C9H12O4
• Molecular Weight: 184.192
• Mol File: 60891-25-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-Cyclohexene-1-carboxylic acid, 3-methoxy-5-oxo-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Cyclohexene-1-carboxylic acid, 3-methoxy-5-oxo-, methyl ester(60891-25-0)
• EPA Substance Registry System: 3-Cyclohexene-1-carboxylic acid, 3-methoxy-5-oxo-, methyl ester(60891-25-0)

Safety Data

• Hazardous Substances Data: 60891-25-0(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 56066-20-7 3-hydroxy-5-oxo-3-cyclohexene-1-carboxylic acid 
• 42858-60-6 3,5-cyclohexanedione-1-carboxylic acid 

Downstream Products

• 60891-22-7 5-(2-Methyl-[1,3]dithiane-2-carbonyl)-3-(2-methyl-[1,3]dithian-2-yl)-cyclohex-2-enone 
• 60891-26-1 3-(2-Methyl-[1,3]dithian-2-yl)-5-oxo-cyclohex-3-enecarboxylic acid methyl ester 
• 72796-29-3 3-acetyl-5-(carbomethoxy)-2-cyclohexen-1-one 
• 72796-31-7 5-(1-Ethanesulfinyl-1-ethylsulfanyl-ethyl)-5-hydroxy-3-methoxy-cyclohex-3-enecarboxylic acid methyl ester 
• 1197361-61-7 3-methoxy-5-methoxycarbonyl-6-(2-nitro-1-phenylethyl)-2-cyclohexen-1-one 

Relevant articles and documents

Alkylation Reactions of 2-Methylpropyl 3-(2-Methylpropoxy)-5-oxocyclohex-3-ene-1-carboxylate

The anion derived from 2-methylpropyl 3-(2-methylpropoxy)-5-oxocyclohex-3-ene-1-carboxylate was reacted with methyl iodide to give cis and trans isomers of 2-methylpropyl 6-methyl-3-(2-methylpropoxy)-5-oxocyclohex-3-ene-1-carboxylate.The reaction proceeded with high regioselectivity.A combination of n.m.r. experiments was used to determine that the major diastereomer was in a trans configuration.The dianion derived from 2-methylpropyl 3-(2-methylpropoxy)-5-oxocyclohex-3-ene-1-carboxylate methylated at C1 and C6 with a roughly equal proportion of cis and trans isomers.When treated with 1 equiv. of 1-bromo-3-chloropropane the same dianion alkylates at C1 to give 2-methylpropyl 1-(3-chloropropyl)-3-(2-methylpropoxy)-5-oxocyclohex-3-ene-1-carboxylate.