60917-29-5

Usage

Uses

Used in Pharmaceutical Industry:
3-Bromo-1,1-difluoropropene is used as an intermediate in the synthesis of organic compounds for the development of new pharmaceuticals. Its high reactivity allows for the creation of complex molecular structures that can address specific medical needs.
Used in Agrochemical Industry:
In the agrochemical sector, 3-Bromo-1,1-difluoropropene is utilized as a key component in the production of pesticides and other crop protection agents. Its ability to participate in multiple types of chemical reactions contributes to the formulation of effective and targeted agrochemicals.
Used in Fine Chemicals Industry:
3-Bromo-1,1-difluoropropene is employed as a reagent in various chemical reactions within the fine chemicals industry. Its versatility in organic synthesis is valuable for creating specialty chemicals used in a wide range of applications, from fragrances to high-performance materials.
It is important to handle 3-Bromo-1,1-difluoropropene with care due to its potential health hazards and flammability, ensuring safe practices in its application across different industries.

Upstream product

• 460-25-3 1,1-difluoro-1,3-dibromopropane 
• 593-60-2 Vinyl bromide 
• 931-91-9 1,1,2,2,3,3-Hexafluoro-cyclopropane 

Relevant academic research and scientific papers

Method of synthesizing fluorinated diene alcohols

Disclosed are fluorinated diene alcohols perferably having a fluorine content of at least about 45 weight percent and having a plurality of moieties of the formula CFx and a plurality of moieties of the formula CHx, where each x is independently 1, 2 or 3 and where each CFx moiety is not directly bonded to another CFx moiety. Methods of synthesizing fluorinated diene alcohol compounds are also disclosed comprising reacting at least one C2-C3 alkene halide with at least one reactant of the formula (II): where Z is OH, OR6, OC(O)R7, or a halogen, R6 is a C1-C6 branched or straight chain alkyl, and R7 is a C1-C6 branched or straight chain alkyl or fluoroalkyl,

gem-(DIFLUOROALLYL)LITHIUM: PREPARATION BY LITHIUM-HALOGEN EXCHANGE AND UTILIZATION IN ORGANOSILICON AND ORGANIC SYNTHESIS.

gem-(Difluoroallyl)lithium may be generated by lithium-bromine exchange between n-butyllithium and CH//2 equals CHCF//2Br at minus 95 degree C by using an in situ procedure. When this preparation is carried out in the presence of chlorosilanes, aldehydes, ketones, and esters, products are formed, often in good yield. The factors determining the regioselectivity in addition to C equals O of unsymmetrically substituted allylic lithium reagents are discussed.

gem-Difluoroallyllithium: Improved Synthesis Brings Improved Applicability

The action of n-butyllithium in hexane on CF2BrCH=CH2/CF2=CHCH2Br (5:2 to 20:1 mixture) in 5:1:1 THF/Et2O/pentane at -95 deg C generates gem-difluoroallyllithium which may be trapped, generally in good yield, by an in situ procedure using triorganochlorosilanes (R3SiCF2CH=CH2) and aldehydes and ketones (RR'C(OH)CF2CH=CH2).

CYCLOPROPANE CHEMISTRY. PART 5 . HEXAFLUOROCYCLOPROPANE AS A SOURCE OF DIFLUOROCARBENE

Thermolysis of hexafluorocyclopropane in the presence of ethylene, propene, vinyl chloride, and vinyl bromide gives good yields of the corresponding 1,1-difluorocyclopropanes, formed by addition of difluorocarbene to the olefin.The tetrafluoroethylene formed dimerises to octafluorocyclobutane, co-dimerises with the olefin, or survives, depending on the reaction conditions.With allene, hexafluorocyclopropane gives 1-(difluoromethylene)cyclopropane, 2,2,3,3-tetrafluorospiropentane, and products derived from tetrafluoroethylene and allene.