6092-19-9Relevant academic research and scientific papers
Solid-phase synthesis of disubstituted N -acylureas from resin-bound ureas and acyl chlorides
Haecker, Hans-Georg,Meusel, Manuela,Aschfalk, Melanie,Guetschow, Michael
experimental part, p. 59 - 64 (2011/04/15)
Acylureas (ureides) are valued for their important biological activities. Whereas cyclic acylureas have frequently been the object of solid-phase chemistry, only few reports have focused on the solid-supported preparation of acyclic representatives. We have prepared different types of acylureas on Rink amide resin in three or four steps. The products are either N-acylated (9, 18), N-acylated-N′-alkylated (10, 19), or N-acylated-N-alkylated (22). Characteristic NMR parameters of isomeric acylureas 10, 19, and 22 are discussed.
Synthesis of nitrogen-containing phenoxyacetic acid derivatives
Yamansarova,Kukovinets,Zainullin,Galin,Abdullin
, p. 546 - 550 (2007/10/03)
Nitrogen-containing phenoxyacetic acid derivatives were synthesized by reactions of substituted phenoxyacetic acids with amines, urea, and ethyl carbamate.
