609339-45-9Relevant academic research and scientific papers
Studies on biological evaluation of cyanopyrans and pyrazolines using microwave assisted synthesis
Kanjariya,Radhakrishnan,Ramchandran,Parekh, Hansa
, p. 1569 - 1573 (2007/10/03)
A series of 3-cyanopyrans 3a-k and pyrazolines 4a-k have been synthesied by condensing 4′-(α-isopropyl-p-chlorophenylacetamidophenyl)-3-aryl-2- propen-1-ones 2 with malononitrile and hydrazine hydrate respectively. Moreover, a simple and efficient method has been deviced for the rapid and improved synthesis of pyrazolines using microwave irradiation (MWI). All the products have been characterised by elemental analyses, IR, 1H NMR, mass spectral study and screened for their antimicrobial activity against several microbes and antitubercular activity against Mycobacterium tuberculosis H 37 Rv.
