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5-CHLORO-2-(METHOXYMETHOXY)PHENYLBORONIC ACID is a chemical compound characterized by the presence of a boronic acid group attached to a phenyl ring, which is substituted with a chlorine atom and two methoxymethoxy groups. This unique structure endows it with versatile reactivity in organic synthesis and medicinal chemistry, making it a valuable reagent for creating carbon-carbon and carbon-heteroatom bonds.

609352-56-9

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609352-56-9 Usage

Uses

Used in Organic Synthesis:
5-CHLORO-2-(METHOXYMETHOXY)PHENYLBORONIC ACID is used as a reagent in organic synthesis for the formation of carbon-carbon and carbon-heteroatom bonds. Its ability to participate in various coupling reactions facilitates the construction of complex molecular structures, which are essential in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 5-CHLORO-2-(METHOXYMETHOXY)PHENYLBORONIC ACID is utilized as a building block for the development of pharmaceuticals. Its reactivity allows for the creation of biologically active molecules with potential therapeutic applications. 5-CHLORO-2-(METHOXYMETHOXY)PHENYLBORONIC ACID's structural diversity and functional group compatibility make it a promising candidate for drug discovery and optimization processes.
Used in Pharmaceutical Development:
5-CHLORO-2-(METHOXYMETHOXY)PHENYLBORONIC ACID is employed in the pharmaceutical industry as a key intermediate in the synthesis of drug candidates. Its unique structural properties and reactivity enable the formation of novel molecular entities with potential therapeutic effects. 5-CHLORO-2-(METHOXYMETHOXY)PHENYLBORONIC ACID's versatility in forming diverse chemical linkages contributes to the discovery of new drugs with improved efficacy and selectivity.
Used in Agrochemical Development:
In agrochemical research, 5-CHLORO-2-(METHOXYMETHOXY)PHENYLBORONIC ACID is used as a precursor for the synthesis of bioactive molecules with pesticidal, herbicidal, or fungicidal properties. Its ability to form stable bonds with various functional groups allows for the development of agrochemicals with enhanced performance and selectivity, contributing to more effective and sustainable crop protection strategies.
Used in Material Science and Polymer Chemistry:
5-CHLORO-2-(METHOXYMETHOXY)PHENYLBORONIC ACID also finds applications in material science and polymer chemistry due to its unique structural properties. It can be incorporated into the design and synthesis of novel polymers and materials with specific properties, such as improved mechanical strength, thermal stability, or functional responsiveness. This opens up opportunities for the development of advanced materials for various industrial applications, including electronics, coatings, and composites.

Check Digit Verification of cas no

The CAS Registry Mumber 609352-56-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,0,9,3,5 and 2 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 609352-56:
(8*6)+(7*0)+(6*9)+(5*3)+(4*5)+(3*2)+(2*5)+(1*6)=159
159 % 10 = 9
So 609352-56-9 is a valid CAS Registry Number.

609352-56-9Downstream Products

609352-56-9Relevant academic research and scientific papers

Combined Directed ortho Metalation/Suzuki-Miyaura cross-coupling strategies. Regiospecific synthesis of chlorodihydroxybiphenyls and polychlorinated biphenyls

Nerdinger,Kendall,Cai,Marchart,Riebel,Johnson,Yin,Henaff,Eltis,Snieckus

, p. 5960 - 5967 (2008/02/09)

(Chemical Equation Presented) The Directed ortho Metalation (DoM)/Suzuki-Miyaura cross-coupling strategy is applied for the regiospecific construction of all isomeric monochloro and selected dichloro and trichloro 2,3-dihydroxybiphenyls (DHBs). The combined methodology highlights iterative DoM processes, hindered Suzuki-Miyaura couplings, and advantages in diversity in approaches from commercial starting materials leading to provision of chloro-DHBs as single isomers in high purity and on a gram scale. The syntheis of several PCBs are also reported.

Polymerization of t-butyl vinyl ether mediated by an aluminum Lewis acid-TrF system and its complex structure-tacticity correlation

Oishi,Yamamoto

, p. 1445 - 1454 (2007/10/03)

A variety of aluminum (aryloxide)s were used with triphenylmethyl fluoride (TrF) initiator for the isoselective cationic polymerization of t-butyl vinyl ether. This contribution discusses the relationship between polymer tacticity and counteranion structure, which changed according to the bulkiness, strength and chirality of the Lewis acid combined with TrF so as to make the ionic pair more interactive in the polymerization process. Newly developed organoaluminum activators, 15 and 22, showed mm = 55-57%, which is a more than 10% increase in mm compared with achiral aluminum compounds.

Directed ortho metalation and Suzuki-Miyaura cross-coupling connections: Regiospecific synthesis of all isomeric chlorodihydroxybiphenyls for microbial degradation studies of PCBs

Nerdinger,Kendall,Marchhart,Riebel,Johnson,Yin,Eltis,Snieckus

, p. 2259 - 2260 (2007/10/03)

Monochloro DHBs 1a-d and 2a-c have been regioselectively synthesised in good overall yields by a combination of directed ortho metalation and Suzuki- Miyaura cross-coupling.

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