5-CHLORO-2-(METHOXYMETHOXY)PHENYLBORONIC ACID

Base Information

• Chemical Name: 5-CHLORO-2-(METHOXYMETHOXY)PHENYLBORONIC ACID
• CAS No.: 609352-56-9
• Molecular Formula: C8H10BClO4
• Molecular Weight: 216.427
• Hs Code.: 2931900090
• Mol file: 609352-56-9.mol

Synonyms:5-CHLORO-2-(METHOXYMETHOXY)PHENYLBORONIC ACID

Chemical Property of 5-CHLORO-2-(METHOXYMETHOXY)PHENYLBORONIC ACID

Chemical Property:

• PSA: 58.92000
• LogP: 0.00250
• Storage Temp.: 2-8°C

Purity/Quality:

95% ^*data from raw suppliers

5-Chloro-2-(methoxymethoxy)phenylboronicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-CHLORO-2-(METHOXYMETHOXY)PHENYLBORONIC ACID

There total 3 articles about 5-CHLORO-2-(METHOXYMETHOXY)PHENYLBORONIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-chloro-4-(methoxymethoxy)benzene (826-26-6) → 2-methoxymethoxy-5-chlorophenylboronic acid (609352-56-9)

Guidance literature:

1-chloro-4-(methoxymethoxy)benzene; With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; In diethyl ether; hexane; at -78 ℃; for 1h;

With Trimethyl borate; In diethyl ether; hexane; at -78 - 20 ℃;

With ammonium chloride; In diethyl ether; hexane; at 20 ℃; pH=6; Further stages.;

DOI:10.1021/jo062543i

Reference yield:

Trimethyl borate (121-43-7,63156-11-6) + 1-chloro-4-(methoxymethoxy)benzene (826-26-6) → 2-methoxymethoxy-5-chlorophenylboronic acid (609352-56-9) + C16H17BCl2O5

Guidance literature:

1-chloro-4-(methoxymethoxy)benzene; With n-butyllithium; In tetrahydrofuran; hexane; at 0 ℃; for 2h;

Trimethyl borate; In tetrahydrofuran; hexane; for 1h;

With water; ammonium chloride; In tetrahydrofuran; hexane; for 1h;

DOI:10.1246/bcsj.74.1445

Reference yield:

C10H14BClO4 → 2-methoxymethoxy-5-chlorophenylboronic acid (609352-56-9)

Guidance literature:

With water;

DOI:10.1039/a907279i

upstream raw materials:

Trimethyl borate

1-chloro-4-(methoxymethoxy)benzene

Downstream raw materials:

C₇H₇ClCH₂O₂BHO₂C₆H₁₀

Refernces

• 1、 Oishi,Yamamoto. "Polymerization of t-butyl vinyl ether mediated by an aluminum Lewis acid-TrF system and its complex structure-tacticity correlation". . p. 1445 - 1454. Retrieved 2007/10/03.