609367-32-0

Upstream product

• 2212-75-1 N₂-[(benzyloxy)carbonyl]-L-lysine 
• 124-40-3 dimethyl amine 
• 2389-60-8 Z-Lys(Boc)-OH 
• 241825-30-9 N₂-[(benzyloxy)carbonyl]-N₆-(tert-butoxycarbonyl)-N,N-dimethyl-L-lysinamide 

Downstream Products

• 1327280-59-0 C₁₇H₂₆N₄O₄ 
• 1327280-60-3 C₃₁H₄₄N₄O₁₃ 
• 1643431-02-0 C₃₁H₄₄N₄O₁₃ 
• 609367-12-6 (R)-2-[(Benzyloxy-formyl-amino)-methyl]-hexanoic acid ((S)-5-amino-1-dimethylcarbamoyl-pentyl)-amide 

Relevant academic research and scientific papers

Protecting group free synthesis of urea-linked glycoconjugates: Efficient synthesis of β-urea glycosides in aqueous solution

A method for the protecting group free synthesis of β-urea-linked glycoconjugates has been developed. The one step process, involving reactions between urea and d-glucose, N-acetyl-d-glucosamine or d-xylose in acidic aqueous solution, furnishes the corresponding β-urea glycosides in modest yields. This simple and efficient procedure is applicable to the synthesis of β-urea tethered amino acid-carbohydrate conjugates. This journal is the Partner Organisations 2014.

Synthesis of urea and carbamate glycosides employing unprotected carbohydrates

A study of methods for the synthesis of urea and carbamate glycosides, starting with unprotective carbohydrates, led to the preparation of amino acid-carbohydrate conjugates in aqueous media. Georg Thieme Verlag Stuttgart - New York.

Structure-activity relationships of the peptide deformylase inhibitor BB-3497: Modification of the P2′ and P3′ side chains

Structural modifications to the peptide deformylase inhibitor BB-3497 are described. In this paper, we describe the initial SAR around this lead for modifications to both the P2′ and P3′ side chains. Enzyme inhibition and antibacterial activity data revealed that a variety of substituents are tolerated at the P2′ and P3′ positions of the inhibitor backbone. The data from this study highlights the potential for modification at the P2′ and P3′ positions to optimise the physicochemical properties.