609789-94-8

Basic information

• Product Name: Phosphonic acid, [(4-cyano-3-fluorophenyl)methyl]-, diethyl ester
• CAS NO: 609789-94-8
• Molecular Formula: C12H15FNO3P
• Molecular Weight: 271.228
• Mol File: 609789-94-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Phosphonic acid, [(4-cyano-3-fluorophenyl)methyl]-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, [(4-cyano-3-fluorophenyl)methyl]-, diethyl ester(609789-94-8)
• EPA Substance Registry System: Phosphonic acid, [(4-cyano-3-fluorophenyl)methyl]-, diethyl ester(609789-94-8)

Safety Data

• Hazardous Substances Data: 609789-94-8(Hazardous Substances Data)

Upstream product

• 78-40-0 triethyl phosphate 
• 105942-09-4 4-(bromomethyl)-3-fluorobenzonitrile 

Relevant articles and documents

BENZAMIDE DERIVATIVES

A compound represented by formula (1): wherein X is a single bond or a substituted or unsubstituted lower alkylene group; Z is a saturated or unsaturated monocyclic hydrocarbon ring group or the like; and each of R1, R2, R3 and R4, which may be the same or different, is a hydrogen atom, a halogen atom, a nitro group, a cyano group, a carboxyl group, a substituted or unsubstituted alkyl group, or the like, a prodrug of said compound, or a pharmaceutically acceptable salt of said compound or prodrug has inhibitory effect on Rho kinase and hence is useful for treating diseases which are such that morbidity due to them is expected to be improved by inhibition of Rho kinase and secondary effects such as inhibition of the Na+/H+ exchange transport system caused by the Rho kinase inhibition, for example, hypertension.