6098-50-6Relevant academic research and scientific papers
Taxines from the needles of Taxus wallichiana
Prasain, Jeevan Kumar,Stefanowicz, Piotr,Kiyota, Taira,Habeichi, Farida,Konishi, Yasuo
, p. 1167 - 1170 (2001)
A taxine, 5αO-(3′-dimethylamino-3′-phenylpropionyl) taxinine M (1) together with two known compounds 7-O-acetyltaxine A (2) and 2α-acetoxy-2′ β-deacetylaustrospicatine (3) were isolated from the needles of the Himalayan yew, Taxus wallichiana Zucc. Their structures were elucidated on the basis of the NMR spectral data, ESI-MS/MS analysis and chemical methods. Compounds 1 and 3 showed moderate cytotoxic activity against the lung cancer cell line A549 in vitro.
