60984-51-2

Upstream product

• 100-52-7 benzaldehyde 
• 108-03-2 1-Nitropropane 
• 344347-13-3 2-nitro-1-phenyl-1-trimethylsilyloxybutane 
• 6329-58-4 Diethyl 1-nitropropanephosphonate 

Downstream Products

• 28612-57-9 4-[8-(2-nitro-1-phenyl-butyl)-cyclooct-1-enyl]-morpholine 
• 61668-44-8 1-phenyl-2-nitrobutane 
• 28612-54-6 3-ethyl-9a-morpholin-4-yl-4-phenyl-4,4a,5,6,7,8,9,9a-octahydro-cyclohepta[e][1,2]oxazine 2-oxide 
• 28557-76-8 3-ethyl-7a-morpholin-4-yl-4-phenyl-4,4a,5,6,7,7a-hexahydro-cyclopenta[e][1,2]oxazine 2-oxide 
• 28612-52-4 3-ethyl-4ξ-phenyl-8a-pyrrolidin-1-yl-(4ar,8at)-4a,5,6,7,8,8a-hexahydro-4H-benzo[e][1,2]oxazine 2-oxide 
• 28612-59-1 4-(2-nitro-1-phenyl-butyl)-morpholine 

Relevant academic research and scientific papers

Asymmetric reduction of nitroalkenes with baker's yeast

Various α,β-disubstituted and trisubstituted nitroalkenes were chemoselectively reduced with baker's yeast to the corresponding nitroalkanes. Stereoselectivities of the reduction of α,β-disubstituted nitroalkenes were modest to low, and e.e.s up to 52% were obtained. Trisubstituted nitroalkenes could be reduced to the corresponding nitroalkanes with excellent enantioselectivities, moderate diastereoselectivities and in good yield.

A modified Horner-Wadsworth-Emmons reaction for the synthesis of nitroalkenes

A range of trisubstituted nitroalkenes are available from the reaction of an α-nitrophosphonate anion and an aldehyde in tetrahydrofuran under reflux.

A New Method for the Preparation of Conjugated Nitro Olefins

Condensation of 1-nitroalkanephosphonates with carbonyl compounds affords a new and facile method for the preparation of conjugated nitro olefins.

PREPARATION OF ACYCLIC NITRO OLEFINS FROM β-TRIMETHYLSILOXY NITRO COMPOUNDS

An efficient process for the preparation of acyclic nitro olefins is described, which consisted of improved nitro aldol reaction to give β-trialkylsiloxy nitro compounds and the direct or indirect elimination of water.