60987-99-7

Basic information

• Product Name: 1-Piperazineacetic acid, 4-phenyl-, 2-[[(4-chlorophenyl)amino]thioxomethyl]hydrazide
• CAS NO: 60987-99-7
• Molecular Formula: C19H22ClN5OS
• Molecular Weight: 403.936
• Mol File: 60987-99-7.mol

Chemical Properties

• CAS DataBase Reference: 1-Piperazineacetic acid, 4-phenyl-, 2-[[(4-chlorophenyl)amino]thioxomethyl]hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperazineacetic acid, 4-phenyl-, 2-[[(4-chlorophenyl)amino]thioxomethyl]hydrazide(60987-99-7)
• EPA Substance Registry System: 1-Piperazineacetic acid, 4-phenyl-, 2-[[(4-chlorophenyl)amino]thioxomethyl]hydrazide(60987-99-7)

Safety Data

• Hazardous Substances Data: 60987-99-7(Hazardous Substances Data)

Upstream product

• 2131-55-7 4-Chlorophenyl isothiocyanate 
• 1689-05-0 4-phenyl-1-piperazineacetic acid hydrazide 
• 56968-26-4 ethyl 2-(4-phenyl-piperarazin-1-yl)acetate 
• 92-54-6 4-phenyl-1-piperazine 

Relevant articles and documents

Synthesis of Novel Triazolyl/Oxadiazolyl/Thiadiazolyl-Piperazine as Potential Anticonvulsant Agents

Reaction of piperazine with chloroacetylchloride in dry acetone yield compound 1, which on reaction with hydrazine hydrate yielded compound 2, which was further reacted with various substituted phenylisothiocyanates in absolute alcohol to afford compounds

Synthesis of substituted piperazinyl semicarbazides and thiosemicarbazide: as possible acetyl cholinesterase (AChE) inhibitors

Some new N'-(N-aryl-N'-acetyl) piperazine-N4-aryl/alkyl semicarbazide and thiosemicarbazides have been synthesised as possible acetyl cholinesterase (AChE) inhibitors, by the condensation of N-aryl N'-piperazine acetic acid hydrazide with aryl or alkyl isocyanate and aryl isothiocyanates.