610-37-7

Basic information

• Product Name: 5-Hydroxy-2-nitrobenzoic acid
• Synonyms: 5-hydroxy-2-nitro-benzoicaci;RARECHEM AL BE 0679;3-carboxy-4-nitrophenol;5-HYDROXY-2-NITROBENZOIC ACID;5-Hydroxy-2-nitrobenzoic acid, tech;2-Nitro-5-hydroxybenzoic acid;5-hydroxy-2-nitrobenzoic acid(SALTDATA: FREE);5-Hydroxy-2-nitrobenzoic
• CAS NO: 610-37-7
• Molecular Formula: C₇H₅NO₅
• Molecular Weight: 183.12
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Carboxylic Acids;Phenyls & Phenyl-Het;Carboxylic Acids;Phenyls & Phenyl-Het
• Mol File: 610-37-7.mol
• Article Data: 15

Chemical Properties

• Melting Point: 170-171°C
• Boiling Point: 455 °C at 760 mmHg
• Flash Point: 209.6 °C
• Appearance: /
• Density: 1.631
• Vapor Pressure: 4.52E-09mmHg at 25°C
• Refractive Index: 1.663
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 2.06±0.25(Predicted)
• CAS DataBase Reference: 5-Hydroxy-2-nitrobenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Hydroxy-2-nitrobenzoic acid(610-37-7)
• EPA Substance Registry System: 5-Hydroxy-2-nitrobenzoic acid(610-37-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• RTECS: DH2528250
• Hazardous Substances Data: 610-37-7(Hazardous Substances Data)

Usage

General Description

5-Hydroxy-2-nitrobenzoic acid is a moderately acid organic compound that belongs to the classification of benzoic acids. These are compounds containing a benzene ring which is attached to a carboxyl group. This particular chemical can also be termed as a monohydroxybenzoic acid with additional nitro and hydroxy substituents positioned at the 2- and 5-locations, respectively. It is a vital raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals, and dyestuff. Providing a yellow crystalline appearance, it can be harmful if inhaled, swallowed, or comes into contact with the skin or eyes. Its CAS registry number is 618-23-9.

InChI:InChI=1/C7H5NO5/c9-4-1-2-6(8(12)13)5(3-4)7(10)11/h1-3,9H,(H,10,11)

Upstream product

• 623-11-0 1-methyl-4-nitrosobenzene 
• 610-28-6 2,5-dinitrobenzoic acid 
• 42454-06-8 2-nitro-5-hydroxybenzaldehyde 
• 99-06-9 3-Carboxyphenol 
• 7697-37-2 nitric acid 
• 98-95-3 nitrobenzene 
• 13280-60-9 5-amino-2-nitrobenzoic acid 
• 4368-83-6 2-nitro-5-acetylaminobenzoic acid 
• 142010-16-0 2-Nitro-5-hydroxycinnamic acid 
• 1882-69-5 5-methoxy-2-nitro-benzoic acid 
• 394-31-0 2-amino-5-hydroxybenzoic acid 
• 2516-95-2 5-chloro-2-nitrobenzoic acid 
• 50594-66-6 acifluorfen 
• 7732-18-5 water 

Downstream Products

• 394-31-0 2-amino-5-hydroxybenzoic acid 
• 61340-14-5 benzyl 5-benzyloxy-2-nitrobenzoate 
• 68701-49-5 isopropyl 5-isopropoxy-2-nitrobenzoate 
• 117207-68-8 tert-butyl 5-hydroxy-2-nitrobenzoate 
• 116027-17-9 2-amino-5-benzyloxybenzoic acid methyl ester 
• 116027-16-8 methyl 5-(benzyloxy)-2-nitrobenzoate 

Relevant articles and documents

Synthesis, properties, and remarkable 2 D self-assembly at the liquid/solid interface of a series of triskele-shaped 5,11,17-triazatrinaphthylenes (TrisK)

A series of 5,11,17-triazatrinaphthylene (TrisK) derivatives, large disk-like π-conjugated molecules with C3h symmetry, has been synthesised by following an optimised synthetic pathway. The synthesis was performed by a four-step protocol based

Oxidative Decomposition of a Mononitrobenzenesulfenate Ion in 15.3 M Potassium Hydroxide via a Stable Meisenheimer Complex

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HETEROCYCLIC COMPOUNDS, PROCESS FOR PREPARATION OF THE SAME AND USE THEREOF

The present invention provides a heterocyclic compound represented by the formula (I), its stereoisomers, or a pharmaceutically acceptable salt thereof, pharmaceutical compositions thereof, and their use in preparing a medicament for the prevention and/or treatment of central nervous system disease.

A practical approach for regioselective mono-nitration of phenols under mild conditions

Cu(NO3)2.3H2O was demonstrated to be an efficient, regioselective and inexpensive nitrating reagent for the synthesis of mono-nitro substituted phenolic compounds. 12 examples of different phenols were examined. Good yields (67-90%) have been achieved. ARKAT-USA, Inc.