6102-15-4

Basic information

• Product Name: 4-Carbethoxy-3,5-diMethyl-2-cyclohexene-1-one
• Synonyms: 3,5-DiMethyl-4-carbethoxy-2-cyclohexen-1-one;4-Carbethoxy-3,5-diMethyl-2-cyclohexene-1-one;ETHYL 2,6-DIMETHYL-4-OXOCYCLOHEX-2-ENECARBOXYLATE
• CAS NO: 6102-15-4
• Molecular Formula: C₁₁H₁₆O₃
• Molecular Weight: 196.24294
• Mol File: 6102-15-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 293.13°C (rough estimate)
• Flash Point: 119.2°C
• Appearance: /
• Density: 1.0493
• Vapor Pressure: 0.00372mmHg at 25°C
• Refractive Index: 1.4773 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-Carbethoxy-3,5-diMethyl-2-cyclohexene-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Carbethoxy-3,5-diMethyl-2-cyclohexene-1-one(6102-15-4)
• EPA Substance Registry System: 4-Carbethoxy-3,5-diMethyl-2-cyclohexene-1-one(6102-15-4)

Safety Data

• Hazardous Substances Data: 6102-15-4(Hazardous Substances Data)

Usage

General Description

4-Carbethoxy-3,5-dimethyl-2-cyclohexene-1-one is an organic compound with a unique chemical structure. It is a cyclic ketone with a carbethoxy group, two methyl groups, and a cyclohexene ring. This chemical is commonly used in the field of organic synthesis and has applications in pharmaceutical and agrochemical industries. It can be synthesized through various methods such as the Claisen condensation reaction or the Friedel-Crafts acylation reaction. Its chemical properties and reactivity make it a valuable building block in the production of complex organic molecules.

InChI:InChI=1/C11H16O3/c1-4-14-11(13)10-7(2)5-9(12)6-8(10)3/h5,8,10H,4,6H2,1-3H3

Upstream product

• 141-97-9 ethyl acetoacetate 
• 74-86-2 acetylene 
• 15301-37-8 3-ethoxycarbonyl-3-penten-2-one 
• 123-63-7 paracetaldehyde 
• 75-07-0 acetaldehyde 

Downstream Products

• 91157-78-7 (1α,2β,6α)-(+/-)-Ethyl 2-Ethenyl-2,6-dimethyl-4-oxocyclohexanecarboxylate 
• 91157-78-7 (1α,2ξ,6β)-(+/-)-Ethyl 2-Ethenyl-2,6-dimethyl-4-oxocyclohexanecarboxylate 
• 2320-30-1 3,5-dimethylcyclohexanone 
• 5441-52-1 3,5-dimethylcyclohexan-1-ol 
• 1097633-92-5 3-diazo-2,6-dimethyl-4-oxo-cyclohex-1-enecarboxylic acid ethyl ester 
• 928312-75-8 4-allyloxy-2,6-dimethyl-3-phenylamino-benzoic acid ethyl ester 
• 93445-26-2 2-butyl-3,5-dimethyl-cyclohex-2-enone 
• 93445-22-8 2-ethyl-3,5-dimethyl-cyclohex-2-enone 
• 67543-92-4 3,5-dimethyl-cyclohex-2-enone oxime 
• 100667-93-4 ethyl 2,6-dimethyl-4-methoxycyclohexa-1,3-dienecarboxylate 
• 139387-18-1 ethyl cis,cis-2,6-dimethylcyclohexan-4-one-1-carboxylate 
• 75056-98-3 ethyl 4-hydroxy-2,6-dimethyl benzoate 
• 116059-86-0 ethyl 2,6-dimethyl-1-(p-methoxyphenyl)-4-oxocyclohex-2-enecarboxylate 
• 116059-87-1 ethyl trans-2,6-dimethyl-3-(p-methoxyphenyl)-4-oxocyclohex-2-enecarboxylate 

Relevant articles and documents

Preparation method of cis, cis-3, 5-dimethyl-1-cyclohexanol

The invention belongs to the field of chemistry, and discloses a synthesis method of a cis, cis-3, 5-dimethyl-1-cyclohexanol compound shown as a formula (I). Acetaldehyde and ethyl acetoacetate are used as raw materials, and cis, cis-3, 5-dimethyl-1-cyclohexanol is synthesized by a series of reactions such as knoevenagel condensation, hydrolysis, decarboxylation, hydrogenation reduction, reduction, acylating chlorination, hydrolysis and the like. The raw materials and auxiliary materials of the route are simple and easily available, the reaction conditions are mild, the operation is simple andconvenient, the synthesis cost is low, and the obtained product has high chiral purity (the product/isomer ratio is 30: 1-100: 1) and is suitable for large-scale production.

High-yielding synthesis of Nefopam analogues (functionalized benzoxazocines) by sequential one-pot cascade operations

An efficient amine-/ruthenium-catalyzed three-step process for the synthesis of Nefopam analogues was achieved through combinations of cascade enamine amination/iso-aromatization/allylation and diene or enyne metathesis as key steps starting from functionalized Hagemann's esters. In this communication, we discovered the application of ruthenium-catalysis on olefins containing free amines without in situ formation of salts.

Highly Efficient Synthesis of Methyl-Substituted Conjugate Cyclohexenones

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