610300-81-7Relevant academic research and scientific papers
t-BuOK-mediated hydrophosphination of functionalized alkenes: A novel synthesis of chiral P,N- and P,P-ligands
Bunlaksananusorn, Tanasri,Knochel, Paul
, p. 4595 - 4601 (2007/10/03)
A novel synthesis of effective chiral P,N- and P,P-ligands has been developed by using a t-BuOK-mediated hydrophosphination of chiral alkenylpyridines and alkenylphosphine oxides. Ir complexes of chiral P,N-ligands 1 and 3 gave high enantioselectivities for the hydrogenation of (Z)-α-(acetamido)cinnamate 25 and (E)-1,2-diphenylpropene leading to the hydrogenated products with up to 97% ee.
