610300-83-9Relevant academic research and scientific papers
Chiral ligands and their transition metal complexes
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, (2008/06/13)
The present invention relates to chiral phosphorus compounds and their transition metal complexes, and also to the use of these transition metal complexes, especially in asymmetric syntheses.
CHIRAL LIGANDS AND THEIR TRANSITION METAL COMPLEXES
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Page/Page column 27, (2010/02/09)
The invention relates to chiral phosphorus compounds and their transition metal complexes, in addition to the use of said transition metal complexes, in particular in asymmetric syntheses.
t-BuOK-mediated hydrophosphination of functionalized alkenes: A novel synthesis of chiral P,N- and P,P-ligands
Bunlaksananusorn, Tanasri,Knochel, Paul
, p. 4595 - 4601 (2007/10/03)
A novel synthesis of effective chiral P,N- and P,P-ligands has been developed by using a t-BuOK-mediated hydrophosphination of chiral alkenylpyridines and alkenylphosphine oxides. Ir complexes of chiral P,N-ligands 1 and 3 gave high enantioselectivities for the hydrogenation of (Z)-α-(acetamido)cinnamate 25 and (E)-1,2-diphenylpropene leading to the hydrogenated products with up to 97% ee.
New P, N ligands for asymmetric Ir-catalyzed reactions
Bunlaksananusorn, Tanasri,Polborn, Kurt,Knochel, Paul
, p. 3941 - 3943 (2007/10/03)
Chiral Ir complexes such as 1 catalyze the hydrogenation of (E)-1, 2-diphenylpropene at 1 bar of H2 to give (5)-1, 2-diphenylpropane with up to 95% ee and full conversion (see scheme). Methyl (Z)-α -(acetamido)cinnamate underwent enantioselective hydrogenation under similar conditions to the corresponding amino acid derivative with up to 96% ee. BARF = tetrakis(3,5-bis(trifluoromethyl)phenyl)borate, cod = 1, 5-cyclooctadiene.
