6104-48-9

Basic information

• Product Name: Phosphine oxide, ethynyldiphenyl-
• CAS NO: 6104-48-9
• Molecular Formula: C14H11OP
• Molecular Weight: 226.215
• Mol File: 6104-48-9.mol

Chemical Properties

• CAS DataBase Reference: Phosphine oxide, ethynyldiphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphine oxide, ethynyldiphenyl-(6104-48-9)
• EPA Substance Registry System: Phosphine oxide, ethynyldiphenyl-(6104-48-9)

Safety Data

• Hazardous Substances Data: 6104-48-9(Hazardous Substances Data)

Upstream product

• 6104-47-8 ethynyldiphenylphosphine 
• 1707-03-5 diphenyl-phosphinic acid 
• 4301-14-8 acetylenemagnesium bromide 
• 18872-86-1 diphenylphosphine oxide 
• 4559-70-0 Diphenylphosphine oxide 
• 108-86-1 bromobenzene 
• 21037-91-2 trimethylsilyl(diphenylphosphanyl)acetylene 
• 1079-66-9 chloro-diphenylphosphine 

Downstream Products

• 89218-14-4 ((E)-2-Diphenylphosphanyl-vinyl)-methyl-(1-phenyl-ethyl)-amine 
• 1351165-67-7 Ethynyldiphenylphosphine oxide 
• 7608-36-8 1,3-bis[(diphenylphosphoryl)ethynyl]benzene 
• 1351165-66-6 [2-(4-bromophenyl)ethynyl]diphenylphosphine oxide 
• 1151549-82-4 4-[2-[3-[2-(4-methoxyphenyl)ethynyl]phenyl]ethynyl]benzonitrile 
• 1351165-68-8 ((3-ethynylphenyl)ethynyl)diphenylphosphine oxide 
• 1351165-79-1 3-(4-methoxyphenylethynyl)phenylethynyldiphenylphosphine oxide 
• 1351165-69-9 1-ethynyl-3-(4-methoxyphenylethynyl)benzene 
• 6224-95-9 diphenyl(1-propynyl)phosphine oxide 

Relevant articles and documents

Process-Controlled Regiodivergent Copper-Catalyzed Azide-Alkyne Cycloadditions: Tailor-made Syntheses of 4- And 5-Bromotriazoles from Bromo(phosphoryl)ethyne

We developed a regiodivergent syntheses of 4- and 5-bromo-substituted 1,2,3-triazoles in copper-catalyzed azide-alkyne cycloadditions (CuAACs) by taking advantage of bromo(phosphoryl)ethyne 1 as a bromoethyne equivalent. A one-shot dephosphorylative CuAAC

Diethyl (iodoethynyl)phosphonate and (iodoethynyl)diphenylphosphane oxide: Crystal structures and some cycloaddition reactions

The title compounds are difunctionalized acetylenic building blocks, which can serve as electrophilic dienophiles and dipolarophiles in [4+2] and azide-iodoalkyne [3+2] cycloaddition reactions, which, however, require strong thermal activation. In their c

General Cu-Catalyzed Csp-S Coupling

Copper-catalyzed cross-coupling of thiols and bromoalkynes affords a mild, rapid, and selective Csp-S coupling with broad scope, enabling the use of aryl-, alkyl-, and silyl-substituted alkynyl coupling partners (38 total examples, 50-99percent yields). Importantly, the method enables the preparation of difficult-to-access bis-heteroatom-functionalized (S,S-, S,P-, and S,N-) alkynes.

Synthesis of Ph2P(O)-stabilized Ynamines via C(sp)-N bond formation and their dephosphorylative copper-catalyzed click reaction

A facile and versatile synthesis of ynamines via C(sp)-N bond formation was established. We installed an electron-withdrawing phosphoryl group onto the ynamines to isolate them by column chromatography. Phosphoryl ynamines were synthesized by treatment of

Phosphine-substituted 1,2,3-triazoles as P,C- And P,N-ligands for photoluminescent coinage metal complexes

A series of homo- and hetero-polynuclear coinage metal complexes based on a phosphine-substituted 1,2,3-triazole system is presented. Besides the P,N-ligand 1-benzyl-4-(diphenylphosphanyl)-1H-1,2,3-triazole (LPN), the P,C-donor ligand 1-benzyl-

Selective P?C(sp3) Bond Cleavage and Radical Alkynylation of α-Phosphorus Alcohols by Photoredox Catalysis

Herein the first P?C(sp3) bond cleavage and radical alkynylation of α-phosphorus alcohols to construct phosphonoalkynes is reported. The phosphorus radical is generated upon P?C bond cleavage reaction via the alkoxyl radical through photoredox catalysis with cyclic iodine(III) reagents. Various arylphosphinoyl-, alkylphosphinoyl-, phosphonate-, and phosphonic amide alcohols serve as radical phosphorus precursors to construct phosphonoalkynes for the first time.

PHOSPHOROUS COMPOUND AND TRANSITION METAL COMPLEX THEREOF

The present invention provides a phosphorous compound represented by general formula (1), and transition metal complexes containing such phosphorous compounds as ligands: wherein R1 to R7, A, B, Y, and Z have the same meanings as those defined in the specification.

Selective deprotection of Me3Si-/Ph2P(O)-protected arylalkynes: Methyl Grignard reagent-promoted dephosphorylation of Ph2P(O)-protected alkynes

A Ph2P(O)-protected alkyne underwent dephosphorylation by treatment with MeMgBr in THF with Me3Si-protection untouched. The dephosphorylation followed by a transition-metal-catalyzed coupling of the resulting terminal a lkyne with aryl halides was carried out in a one-pot manner to afford the desired coupling product. Selective deprotection of Me3Si-/Ph2P(O)-protected alkynes enabled facile syntheses of expanded π-systems such as cyclic phenyleneethyny lenes and unsymmetrically substituted ditriazol.

One-pot transformation of Ph2P(O)-protected ethynes: Deprotection followed by transition metal-catalyzed coupling

Ph2P(O)-protected ethynes were successfully transformed to arylethynes in one-pot manner through t-BuOK-catalyzed deprotection followed by Sonogashira coupling with aryl halide. The arylethynes were obtained similarly by Ph2P(O)-deprotection, stannylation of the resulting terminal ethynes, and Migita-Kosugi-Stille coupling. Deprotection followed by intramolecular Eglinton coupling could be carried out in one-pot to provide cyclic butadiynes.

Ph(O) group for protection of terminal acetylenes

A protecting group Ph(O) for terminal ethyne was newly developed. This protecting group can be introduced readily to terminal ethyne by CuI-catalyzed phosphination and subsequent oxidation with H Ph(O)-protected ethynes remained intact in Sonogashira coup