61040-21-9

Basic information

• Product Name: Serine, 3-ethoxy-O-ethyl-, ethyl ester
• Synonyms: Serine, 3-ethoxy-O-ethyl-, ethyl ester
• CAS NO: 61040-21-9
• Molecular Formula: C₉H₁₉NO₄
• Molecular Weight: 205.25146
• Mol File: 61040-21-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Serine, 3-ethoxy-O-ethyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Serine, 3-ethoxy-O-ethyl-, ethyl ester(61040-21-9)
• EPA Substance Registry System: Serine, 3-ethoxy-O-ethyl-, ethyl ester(61040-21-9)

Safety Data

• Hazardous Substances Data: 61040-21-9(Hazardous Substances Data)

Usage

General Description

Serine, 3-ethoxy-O-ethyl-, ethyl ester is a chemical compound that is derived from serine, an amino acid that is important for the synthesis of proteins in the body. The ethyl ester derivative of serine is often used as a building block in the synthesis of various pharmaceutical compounds, including antiviral and anticancer drugs. It is also used in the production of certain flavors and fragrances. Serine, 3-ethoxy-O-ethyl-, ethyl ester is a clear, colorless liquid with a slightly sweet odor, and it is soluble in water and most organic solvents. Serine, 3-ethoxy-O-ethyl-, ethyl ester is primarily used in research and industrial applications, and it should be handled and used with caution due to its potential health hazards.

Upstream product

• 3154-51-6 ethyl N-formylglycinate 
• 64-17-5 ethanol 
• 109-94-4 formic acid ethyl ester 
• 134936-23-5 ethyl (R/S)-2-(dibenzylamino)-3,3-diethoxypropionate 
• 187842-16-6 ethyl 3,3-diethoxy-2-nitropropanoate 
• 122-51-0 orthoformic acid triethyl ester 
• 134936-21-3 ethyl (R/S)-2-(dibenzylamino)-3-hydroxy-2-propenoate 

Downstream Products

• 134936-24-6 ethyl (R/S)-2-<(benzyloxyethyl)amino>-3,3-diethoxypropionate 
• 2655-73-4 3,3-Diethoxy-2--propan-1-ol 
• 2655-74-5 2-(N-Benzoylamino)-3-benzoyloxy-propanal-diethylacetal 
• 134936-25-7 ethyl (R/S)-2--3,3-diethoxypropionate 
• 134936-26-8 ethyl (R/S)-2--3,3-diethoxypropionate 

Relevant articles and documents

CONSTRAINED COMPOUNDS AS CGRP-RECEPTOR ANTAGONISTS

The invention encompasses constrained bicyclic and tricyclic CGRP-receptor antagonists, methods for identifying them, pharmaceutical compositions comprising them, and methods for their use in therapy for treatment of migraine and other headaches, neurogenic vasodilation, neurogenic inflammation, thermal injury, circulatory shock, flushing associated with menopause, airway inflammatory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), and other conditions the treatment of which can be effected by the antagonism of CGRP-receptors.

Synthesis of serine analogues to be used as modified phospho acceptor sites in substrates of protein kinase C

Serine and threonine analogues (compounds 2-6) are readily accessible by reaction of the anion of N,N-dibenzylglycine ethyl ester (1) with an appropriate carbonyl compound.These analogues will be incorporated into Protein Kinase C (PKC) substrates.The serine aldehyde derivative 7 was used for the preparation of the corresponding diethyl acetal 9.This compound was the starting material in the synthesis of the suicide precursor 8, featuring a reductive amination leading to 12 and a Lewis-acid-catalysed cyclization giving 8.