61040-21-9

Usage

Uses

Used in Pharmaceutical Industry:
Serine, 3-ethoxy-O-ethyl-, ethyl ester is used as a building block for the synthesis of pharmaceutical compounds, specifically for the development of antiviral and anticancer drugs. Its unique structure allows it to be a valuable component in creating effective medications targeting a range of diseases.
Used in Flavor and Fragrance Industry:
In addition to its pharmaceutical applications, Serine, 3-ethoxy-O-ethyl-, ethyl ester is also utilized in the production of certain flavors and fragrances. Its slightly sweet odor makes it a suitable candidate for use in the creation of various scent profiles and taste enhancements.
Used in Research Applications:
Serine, 3-ethoxy-O-ethyl-, ethyl ester plays a significant role in research settings, where it is employed to study the properties and potential uses of serine and its derivatives. This helps scientists and researchers to better understand the compound's behavior and its interactions with other molecules, leading to advancements in both medicine and other industries.

Upstream product

• 3154-51-6 ethyl N-formylglycinate 
• 64-17-5 ethanol 
• 109-94-4 formic acid ethyl ester 
• 134936-21-3 ethyl (R/S)-2-(dibenzylamino)-3-hydroxy-2-propenoate 
• 122-51-0 orthoformic acid triethyl ester 
• 134936-23-5 ethyl (R/S)-2-(dibenzylamino)-3,3-diethoxypropionate 
• 187842-16-6 ethyl 3,3-diethoxy-2-nitropropanoate 

Downstream Products

• 2655-74-5 2-(N-Benzoylamino)-3-benzoyloxy-propanal-diethylacetal 
• 2655-73-4 3,3-Diethoxy-2--propan-1-ol 
• 134936-25-7 ethyl (R/S)-2--3,3-diethoxypropionate 
• 134936-26-8 ethyl (R/S)-2--3,3-diethoxypropionate 
• 134936-22-4 ethyl (2R/S,3R/S)-4-benzoyl-2-ethoxymorpholine-3-carboxylate 
• 134936-27-9 ethyl 4-benzoyl-5,6-dihydro-1,4-oxazine-3-carboxylate 
• 120105-80-8 3--1,4-dimethylcarbazole 
• 153780-29-1 ethyl 2-<1-(p-toluenesulfonylpyrrol-2-yl)methyl>amino-3,3-diethoxypropionate 
• 153780-31-5 ethyl 2,3-dihydro-1-(p-toluenesulfonyl)pyrrolo<2,3-c>pyridine-5-carboxylate 
• 153780-32-6 ethyl 4,5,6,7-tetrahydro-1-(p-toluenesulfonyl)pyrrolo<2,3-c>pyridine-5-carboxylate 
• 153780-30-4 ethyl 1-(p-toluenesulfonyl)pyrrolo<2,3-c>pyridine-5-carboxylate 
• 147503-82-0 ethyl 1H-pyrrolo[2,3-c]pyridine-5-carboxylate 

Relevant academic research and scientific papers

CONSTRAINED COMPOUNDS AS CGRP-RECEPTOR ANTAGONISTS

The invention encompasses constrained bicyclic and tricyclic CGRP-receptor antagonists, methods for identifying them, pharmaceutical compositions comprising them, and methods for their use in therapy for treatment of migraine and other headaches, neurogenic vasodilation, neurogenic inflammation, thermal injury, circulatory shock, flushing associated with menopause, airway inflammatory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), and other conditions the treatment of which can be effected by the antagonism of CGRP-receptors.

Ethyl α-amino-β,β-diethoxypropionate, a useful synthon for the preparation of 3,4-fused pyridine-6-carboxylates from aromatic aldehydes

An efficient synthesis of ethyl α-amino-β,β-diethoxypropionate (1), via a titanium tetrachloride-catalyzed coupling reaction of ethyl nitroacetate and triethyl orthoformate, is described. Condensation of 1 with various aldehydes followed by reduction and

Synthesis of serine analogues to be used as modified phospho acceptor sites in substrates of protein kinase C

Serine and threonine analogues (compounds 2-6) are readily accessible by reaction of the anion of N,N-dibenzylglycine ethyl ester (1) with an appropriate carbonyl compound.These analogues will be incorporated into Protein Kinase C (PKC) substrates.The serine aldehyde derivative 7 was used for the preparation of the corresponding diethyl acetal 9.This compound was the starting material in the synthesis of the suicide precursor 8, featuring a reductive amination leading to 12 and a Lewis-acid-catalysed cyclization giving 8.